343326-48-7

Upstream product

• 343326-42-1 (3R)- and (3S)-di-(-)-menthyl 3-dimethylphosphoryl-1,2,3,6-tetrahydropyridazine-1,2-dicarboxylate 
• 343326-44-3 (R)-3-(Dimethoxy-phosphoryl)-tetrahydro-pyridazine-1,2-dicarboxylic acid bis-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl) ester 

Relevant academic research and scientific papers

Synthesis of novel (R)- and (S)-piperidazine-3-phosphonic acids and transformation into (R)- and (S)-pyrrolidine-2-phosphonic acids

The first synthesis of a pair of (R)- and (S)-piperidazine-3-phosphonic acids was performed via a one-pot process of hetero Diels-Alder reaction and Lewis acid-catalyzed phosphonylation. The absolute configuration of the target compounds was established b