34334-04-8

Usage

Uses

Used in Organic Synthesis:
4-(2-Morpholin-4-ylethoxy)benzonitrile is utilized as a reagent in organic synthesis for its ability to act as a building block for creating a variety of biologically active compounds. Its structural components allow for the development of new organic molecules with potential applications in various fields.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 4-(2-Morpholin-4-ylethoxy)benzonitrile is employed as a key component in the research and development of new drugs. Its unique properties and potential pharmacological activity make it a promising candidate for the creation of innovative therapeutic agents.
Used in Drug Discovery:
4-(2-Morpholin-4-ylethoxy)benzonitrile is used as a starting material in drug discovery processes, where its morpholine group and nitrile functionality can be leveraged to design and synthesize novel drug candidates with potential therapeutic benefits.
Used in Chemical Biology Research:
4-(2-MORPHOLIN-4-YLETHOXY)BENZONITRILE is also used as a tool in chemical biology research, where it can be employed to study the interactions between small molecules and biological targets, contributing to a better understanding of disease mechanisms and the development of targeted therapies.
Used in Disease Treatment Research:
4-(2-Morpholin-4-ylethoxy)benzonitrile has been studied for its potential use in the treatment of certain diseases, capitalizing on its unique structural features and pharmacological properties to explore its therapeutic potential in various medical conditions.

InChI:InChI=1/C13H16N2O2/c14-11-12-1-3-13(4-2-12)17-10-7-15-5-8-16-9-6-15/h1-4H,5-10H2

Upstream product

• 622-40-2 2-(morpholin-4-yl)ethanol 
• 767-00-0 4-cyanophenol 
• 3240-94-6 N-(2-chlorethyl)morpholine 
• 3647-69-6 4-(2-chloroethyl)morpholine hydrochride 
• 140836-69-7 4-[2-(4-morpholinyl)ethoxy]benzenemethanamine 

Downstream Products

• 49773-05-9 4-{2-[4-(5-pyridin-3-yl-[1,2,4]oxadiazol-3-yl)-phenoxy]-ethyl}-morpholine 
• 140836-69-7 4-[2-(4-morpholinyl)ethoxy]benzenemethanamine 
• 938364-87-5 2-(2-(4-(2-morpholinoethoxy)phenyl)thiazol-4-yl)acetic acid 
• 1339961-98-6 N-benzyl-2-(2-(4-(2-morpholinoethoxy)phenyl)thiazol-4-yl)acetamide 
• 1339961-99-7 N-(4-fluorobenzyl)-2-(2-(4-(2-morpholinoethoxy)phenyl)thiazol-4-yl)acetamide 
• 1339962-00-3 N-(2-chlorobenzyl)-2-(2-(4-(2-morpholinoethoxy)phenyl)thiazol-4-yl)acetamide 
• 1339962-01-4 N-(3,4-dichlorobenzyl)-2-(2-(4-(2-morpholinoethoxy)phenyl)thiazol-4-yl)acetamide 
• 1339962-02-5 N-(4-methylbenzyl)-2-(2-(4-(2-morpholinoethoxy)phenyl)thiazol-4-yl)acetamide 
• 938325-32-7 4-(2-morpholinoethoxy)benzothioamide 
• 1339961-97-5 ethyl 2-(2-(4-(2-morpholinoethoxy)phenyl)thiazol-4-yl)acetate 
• 1019119-71-1 4-(2-morpholin-4-yl-ethoxy)-benzamidine 

Relevant academic research and scientific papers

Synthesis of nitriles from amines using nanoscale Co3O4-based catalysts via sustainable aerobic oxidation

The selective oxidation of amines for the benign synthesis of nitriles under mild conditions is described. Key to success for this transformation is the application of reusable cobalt oxide-based nanocatalysts. The resulting nitriles constitute key precursors and central intermediates in organic synthesis.

"Nanorust"-catalyzed benign oxidation of amines for selective synthesis of nitriles

Organic nitriles constitute key precursors and central intermediates in organic synthesis. In addition, nitriles represent a versatile motif found in numerous medicinally and biologically important compounds. Generally, these nitriles are synthesized by traditional cyanation procedures using toxic cyanides. Herein, we report the selective and environmentally benign oxidative conversion of primary amines for the synthesis of structurally diverse aromatic, aliphatic and heterocyclic nitriles using a reusable "nanorust" (nanoscale Fe2O3)-based catalysts applying molecular oxygen.

Thiazolyl N-benzyl-substituted acetamide derivatives: Synthesis, Src kinase inhibitory and anticancer activities

KX2-391 (KX-01/Kinex Pharmaceuticals), N-benzyl-2-(5-(4-(2- morpholinoethoxy)phenyl)pyridin-2-yl)acetamide, is a highly selective Src substrate binding site inhibitor. To understand better the role of pyridine ring and N-benzylsubstitution in KX2-391 and

Chemically-tagged Mitsunobu reagents for use in solution-phase chemical library synthesis

A general method for high-throughput product purification of Mitsunobu reactions is described. Tagged phosphine and azodicarboxylate reagents are used to synthesize individual library members in solution-phase. Workup and purification are easily accomplished by post-reaction sequestration of the tagged reagents and reagent byproducts by a complementary functionalized ion exchange resin. The reagents are utilized in a 3 step library synthesis.

Method for inhibiting neoplastic cells and related conditions by exposure to substituted N- arylmethyl and heterocyclmethyl-1H-pyrazolo (3,4-B) quinolin-4-amines

A method for inhibiting neoplastic cells and related conditions by exposing them to substituted N-arylmethyl and heterocyclmethyl-1H-pyrazolo?3,4-B!quinolin-4-amines.

Substituted N-arylmethyl and heterocyclmethyl-1H-pyrazolo[3,4-b]quinolin-4-amines and compositions and methods of use thereof

Substituted N-arylmethyl and heterocyclylmethyl-1H-pyrazolo[3,4-b]quinolin-4-amines, pharmaceutical compositions containing them and methods for a) effecting c-GMP-phosphodiesterase inhibition, b) treating heart failure and/or hypertension, c) reversing o