34352-86-8

Basic information

• Product Name: Benzene, 1-(1-methylethenyl)-4-(2-methylpropyl)-
• CAS NO: 34352-86-8
• Molecular Formula: C13H18
• Molecular Weight: 174.286
• Mol File: 34352-86-8.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(1-methylethenyl)-4-(2-methylpropyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(1-methylethenyl)-4-(2-methylpropyl)-(34352-86-8)
• EPA Substance Registry System: Benzene, 1-(1-methylethenyl)-4-(2-methylpropyl)-(34352-86-8)

Safety Data

• Hazardous Substances Data: 34352-86-8(Hazardous Substances Data)

Upstream product

• 38861-78-8 1-(4-isobutyl-phenyl)-ethanone 
• 2065-66-9 methyl-triphenylphosphonium iodide 
• 4167-74-2 4-isobutylphenol 
• 538-93-2 1-phenyl-2-methylpropane 
• 313219-88-4 acetic acid 4-diazo-2-(4-isobutyl-phenyl)-2-methyl-3-oxo-butyl ester 
• 313219-87-3 3-acetoxy-2-(4-isobutyl-phenyl)-2-methyl-propionic acid 
• 313219-79-3 acetic acid 2-chlorocarbonyl-2-(4-isobutyl-phenyl)-propyl ester 
• 313219-89-5 1-diazo-4-hydroxy-3-(4-isobutyl-phenyl)-3-methyl-butan-2-one 
• 93469-76-2 3-hydroxy-2-(4-isobutyl-phenyl)-2-methyl-propionic acid 
• 51146-57-7 (R)-ibuprofene 
• 313219-80-6 4-(4-isobutyl-phenyl)-4-methyl-dihydro-furan-3-one 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 34352-77-7 2-(4-Isobutylphenyl)-2-propanol 
• 145624-60-8 10-isopropenyl-9-oxa-10-borabicyclo<3.3.2>decane 

Downstream Products

• 182816-13-3 1-bromo-2-(4-isobutylphenyl)propan-2-ol 
• 182816-09-7 1-bromo-2-fluoro-2-(4-isobutylphenyl)propane 
• 159850-44-9 (S)-2-(4-isobutylphenyl)-1,2-propanediol 
• 171417-12-2 (R)-2-(p-isobutylphenyl)-1,2-propanediol 
• 235096-17-0 (R)-p-isobutyl-α-methylstyrene oxide 
• 1424343-26-9 2-(4-isobutylphenyl)prop-2-en-1-ol 
• 51407-46-6 2-(4-isobutylphenyl)propionaldehyde 
• 36039-36-8 2-(4-isobutylphenyl)propan-1-ol 
• 180293-49-6 2-fluoro-2-[4-(2-methylpropyl)phenyl]propionic acid 
• 182816-16-6 2-fluoro-2-(4-isobutylphenyl)propyl acetate 
• 182816-19-9 2-fluoro-2-(4-isobutylphenyl)propanol 
• 56374-24-4 (R/S)-4-isobutyl-α-methylstyrene oxide 
• 38861-78-8 1-(4-isobutyl-phenyl)-ethanone 
• 133868-69-6 (S)-(-)-2-(4-isobutylphenyl)propionitrile 

Relevant articles and documents

Metal-Free Deoxygenation of Chiral Nitroalkanes: An Easy Entry to α-Substituted Enantiomerically Enriched Nitriles

A metal-free, mild and chemodivergent transformation involving nitroalkanes has been developed. Under optimized reaction conditions, in the presence of trichlorosilane and a tertiary amine, aliphatic nitroalkanes were selectively converted into amines or nitriles. Furthermore, when chiral β-substituted nitro compounds were reacted, the stereochemical integrity of the stereocenter was maintained and α-functionalized nitriles were obtained with no loss of enantiomeric excess. The methodology was successfully applied to the synthesis of chiral β-cyano esters, α-aryl alkylnitriles, and TBS-protected cyanohydrins, including direct precursors of four active pharmaceutical ingredients (ibuprofen, tembamide, aegeline and denopamine).

Palladium-catalyzed oxidative allylation of bis[(pinacolato)boryl]methane: Synthesis of homoallylic boronic esters

A palladium-catalyzed oxidative allylation of bis[(pinacolato)boryl]methane to afford the corresponding homoallylic organoboronic esters with moderate to excellent yields is reported. This novel transformation provides an efficient strategy for the construction of homoallylic organoboronic esters in one step with a broad substrate scope. It is proposed that the palladium-catalyzed oxidative allylic C-H bond activation process may be involved in the catalytic cycle.

Unexpected extension of usage of PPh3/CBr4, a versatile reagent: Isomerization of aromatic allylic alcohols

The PPh3/CBr4-catalyzed isomerization of 2-aromatic allylic alcohols into the corresponding saturated aldehydes or ketones has been achieved at room temperature in good to excellent yields under mild and metal-free conditions. This new methodology has been applied successfully to the synthesis of ibuprofen in four steps.