343569-07-3

Basic information

• Product Name: 3-(3-methyl-3H-imidazol-4-yl)-3-oxo-2-(triphenyl-λ⁵-phosphanylidene)propionic acid tert-butyl ester
• Synonyms: 3-(3-methyl-3H-imidazol-4-yl)-3-oxo-2-(triphenyl-λ⁵-phosphanylidene)propionic acid tert-butyl ester
• CAS NO: 343569-07-3
• Molecular Weight: 484.535
• Mol File: 343569-07-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(3-methyl-3H-imidazol-4-yl)-3-oxo-2-(triphenyl-λ⁵-phosphanylidene)propionic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-methyl-3H-imidazol-4-yl)-3-oxo-2-(triphenyl-λ⁵-phosphanylidene)propionic acid tert-butyl ester(343569-07-3)
• EPA Substance Registry System: 3-(3-methyl-3H-imidazol-4-yl)-3-oxo-2-(triphenyl-λ⁵-phosphanylidene)propionic acid tert-butyl ester(343569-07-3)

Safety Data

• Hazardous Substances Data: 343569-07-3(Hazardous Substances Data)

Upstream product

• 17289-20-2 methyl 1-methyl-1H-imidazole-5-carboxylate 
• 41806-40-0 1-methyl-1H-imidazole-5-carboxylic acid 
• 86302-43-4 (tert-Butoxycarbonylmethylene)triphenylphosphorane 
• 343569-06-2 1-methyl-5-imidazolecarboxylic acid chloride hydrochloride 

Relevant articles and documents

Synthesis of xestomanzamines a and b

Synthetic pathways are described for the synthesis of two naturally occurring β-carbolines, xestomanzamine A and B. The synthesis of aromatic xestomanzamine A was most conveniently achieved by way of a Grignard reaction in dichloromethane. This route is suitable for the synthesis of analogues with modifications in the imidazole ring of xestomanzamine A. Xestomanzamine B, an oxidation-sensitive dihydro-β-carboline, was prepared by Pictet-Spengler condensation of tryptamine with a vicinal tricarbonyl substituted imidazole.