34357-58-9 Usage
General Description
1,7-Diazaspiro[4.4]nonane, also known as desmethylclozapine, is a chemical compound that belongs to the class of spiro compounds. It is a derivative of clozapine, a widely used antipsychotic medication. 1,7-Diazaspiro[4.4]nonane has been found to have antipsychotic and sedative effects in animal studies, and it has been studied for its potential use in treating schizophrenia and other neuropsychiatric disorders. Its spiro structure is believed to contribute to its unique pharmacological properties, and it is being investigated as a potential new drug candidate for the treatment of mental health disorders. Further research is needed to fully understand the mechanisms of action and potential therapeutic uses of 1,7-Diazaspiro[4.4]nonane.
Check Digit Verification of cas no
The CAS Registry Mumber 34357-58-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,4,3,5 and 7 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 34357-58:
(7*3)+(6*4)+(5*3)+(4*5)+(3*7)+(2*5)+(1*8)=119
119 % 10 = 9
So 34357-58-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H14N2/c1-2-7(9-4-1)3-5-8-6-7/h8-9H,1-6H2
34357-58-9Relevant academic research and scientific papers
Quinolone Antibacterial Agents Substituted at the 7-Position with Spiroamines. Synthesis and Structure-Activity Relationships
Culbertson, Townley P.,Sanchez, Joseph P.,Gambino, Laura,Sesnie, Josephine A.
, p. 2270 - 2275 (2007/10/02)
A series of fluoroquinolone antibacterials having the 7-position (10-position of pyridobenzoxazines) substituted with 2,7-diazaspirononane (4b), 1,7-diazaspirononane (5a), or 2,8-diazaspiroundecane (6b) was prepared, and their biological activities were compared with piperazine and pyrrolidine substituted analogues.Most exhibited potent Gram-positive and Gram-negative activity, especially when side chain 4b was N-alkylated.
