343604-87-5Relevant academic research and scientific papers
Nucleophilic substitution reaction on the nitrogen of indole nucleus: A novel synthesis of 1-aryltryptamines
Hayashi, Toshikatsu,Peng, Wu,Nakai, Yu Ya,Yamada, Koji,Somei, Masanori
, p. 421 - 424 (2007/10/03)
1-Hydroxytryptamine derivatives undergo nucleophilic substitution reaction on the indole nitrogen (Na) as a general reaction by the treatment with acid, providing a novel synthetic method for 1-aryltryptamines. Depending on the structures of nucleophiles,
Nucleophilic substitution reaction on the nitrogen of indole nucleus: Formation of 1-(indol-3-yl)indoles upon reaction of 1-hydroxyindoles with indole in formic acid
Somei, Masanori,Yamada, Fumio,Hayashi, Toshikatsu,Goto, Aya,Saga, Yoshitomo
, p. 457 - 460 (2007/10/03)
1-(Indol-3-yl)indoles are obtained in excellent to good yields by the reaction of 1-hydroxyindoles with indole in 85% formic acid. Their structures are determined by X-Ray crystallographic analysis and chemical correlations. The unprecidented SN2 mechanis
