343614-64-2Relevant academic research and scientific papers
Efficient Asymmetric Synthesis of α-Trifluoromethyl-Substituted Primary Amines via Nucleophilic 1,2-Addition to Trifluoroacetaldehyde SAMP- or RAMP-Hydrazone
Enders, Dieter,Funabiki, Kazumasa
, p. 1575 - 1577 (2007/10/03)
matrix presented An efficient asymmetric synthesis of α-trifluoromethyl-substituted primary amines via nucleophilic 1,2-addition of alkyllithium reagents to trifluoroacetaldehyde SAMP- or RAMP-hydrazone followed by benzoylation and Sml2-promoted nitrogen-nitrogen single bond cleavage is described.
