343614-73-3Relevant articles and documents
Solvent-free stereoselective synthesis of (E)-trifluoromethyl imines and hydrazones
Carroccia, Laura,Fioravanti, Stefania,Pellacani, Lucio,Tardella, Paolo A.
experimental part, p. 4096 - 4100 (2011/02/21)
A new, green and efficient strategy for the synthesis of trifluoromethyl ketimines, aldimines, and hydrazones starting from the corresponding trifluoromethyl carbonyl compounds or their hemiacetals is reported. The condensation reactions were performed under solvent-free conditions with a range of amines or hydrazines and proceeded with high stereoselectivity, always giving only the E-isomer in very good yields. Georg Thieme Verlag Stuttgart - New York.
