343616-01-3

Upstream product

• 591-22-0 3,5-Lutidine 
• 343616-28-4 (S)-piperidine-2-carboxylic acid (4-phenyl-butyl)-amide 
• 7778-42-9 sulphamoyl chloride 
• 343615-63-4 1-(3,4,5-Trimethoxy-phenylsulfamoyl)-piperidine-2S-carboxylic acid 
• 24313-88-0 3,4,5-Trimethoxyaniline 

Relevant academic research and scientific papers

An efficient synthesis of sulfamides

Here we report an efficient synthesis of sulfamides. 3,5-Lutidine was found to be an optimal solvent and catalyst for the reaction. The method was developed during our efforts to synthesize a series of novel FKBP-12 inhibitors in which the known ketoamide linker was replaced with sulfamide.

Compounds, compositions, and methods for stimulating neuronal growth and elongation

The present invention concerns methods, pharmaceutical compounds, and compositions for stimulating neuroite outgrowth in nerve cells leading to nerve regeneration. These methods, compounds and compositions inhibit rotamase enzyme activity associated with binding proteins.