Basic information

Product Name: NS 3623
Synonyms: NS 3623;1-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]-3-[3-(trifluoromethyl)phenyl]urea
CAS NO:343630-41-1
Molecular Formula: C15H10BrF3N6O
Molecular Weight: 427.1787096
EINECS: N/A
Product Categories: Agonist, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File: 343630-41-1.mol

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: /
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: NS 3623(CAS DataBase Reference)
NIST Chemistry Reference: NS 3623(343630-41-1)
EPA Substance Registry System: NS 3623(343630-41-1)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 343630-41-1(Hazardous Substances Data)

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SDS
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343630-41-1 Usage

Uses

Used in Pharmaceutical Industry:
NS 3623 is used as an IKr agonist for studying the effects of hERG channel activation on cardiac repolarization and the potential risks associated with QT interval prolongation. This application is crucial for understanding the safety profiles of drugs and their potential cardiac side effects.
Used in Research and Development:
NS 3623 is used as a research tool in the development of new drugs and therapies targeting the hERG potassium channel. By studying the effects of NS 3623 on the channel, researchers can gain insights into the mechanisms underlying QT interval prolongation and develop strategies to mitigate the associated risks.
Used in Cardiology:
NS 3623 is used as a diagnostic agent in cardiology to assess the potential cardiotoxic effects of drugs on the hERG channel and the subsequent impact on cardiac repolarization. This information is vital for evaluating the safety of medications and identifying potential drug-drug interactions that could lead to life-threatening cardiac events.

Check Digit Verification of cas no

The CAS Registry Mumber 343630-41-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,3,6,3 and 0 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 343630-41:
(8*3)+(7*4)+(6*3)+(5*6)+(4*3)+(3*0)+(2*4)+(1*1)=121
121 % 10 = 1
So 343630-41-1 is a valid CAS Registry Number.

343630-41-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name	1-[4-Bromo-2-(1H-tetrazol-5-yl)phenyl]-3-[3-(trifluoromethyl)phen yl]ure

1.2 Other means of identification

Product number	-
Other names	-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:343630-41-1 SDS

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