34365-88-3Relevant academic research and scientific papers
Asymmetric reduction of nitroalkenes with baker's yeast
Kawai, Yasushi,Inaba, Yoshikazu,Tokitoh, Norihiro
, p. 309 - 318 (2007/10/03)
Various α,β-disubstituted and trisubstituted nitroalkenes were chemoselectively reduced with baker's yeast to the corresponding nitroalkanes. Stereoselectivities of the reduction of α,β-disubstituted nitroalkenes were modest to low, and e.e.s up to 52% were obtained. Trisubstituted nitroalkenes could be reduced to the corresponding nitroalkanes with excellent enantioselectivities, moderate diastereoselectivities and in good yield.
REDUCTION OF AROMATIC NITROALKENES WITH BAKER'S YEAST
Takeshita, Mitsuhiro,Yoshida, Sachiko,Kohno, Yoichiro
, p. 553 - 562 (2007/10/02)
Aromatic nitroalkenes were reduced chemoselectively with baker's yeast to give the corresponding nitroalkanes.
Mass spectrometric investigations on phenylacetic acid derivatives, IV: Loss of ortho-substituents from ionized phenyl-2-propanones upon electron impact
Striegel,Mayer,Wiegrebe,Schlunegger,Siegrist,Aebi
, p. 751 - 760 (2007/10/02)
In the gas phase, the phenyl-2-propanone molecules 2a-4a lose upon electron impact chloro-, bromo-, and iodo-radicals specifically at the orthopOsition of the phenyl group giving rise to strong (M-Hal.)+-ions (70/12 eV; 1st and 2nd FFR) of identical structure as confirmed by their MIKE-CAD-spectra. The daughter ions at m/z 133 from o-chlorophenyl-2-propanone (2a) and 2,2-dimethyl-2,3-dihydro[b]furane (11) are structurally similar but not identical (similarity index 99.8). The collisionally activated (2nd FFR) (M-Br.)+-ions from o-bromophenyl-2-propanone (3a) and 1-bromo-1-phenyl-2-propanone (12) produce virtually congruent spectra. The most impOrtant subsequent fragmentation of the (M-Hal-)+-ions from 2a-4a is the loss of CO which incorporates the C-atom of the carbonyl group exclusively (13C labelling). Mechanistic aspects of the fragmentation sequences are discussed (Figs. 5 and 8).
