343777-46-8 Usage
Uses
Used in Organic Synthesis:
2,2,2-Trifluoro-1-(4-methoxy-3-methyl-phenyl)-ethanol is used as a reagent in organic synthesis, facilitating the creation of a range of chemical compounds due to its unique structural features.
Used in Pharmaceutical Production:
2,2,2-Trifluoro-1-(4-methoxy-3-methyl-phenyl)-ethanol serves as a building block in the production of pharmaceuticals, where its specific functional groups can be incorporated into the molecular structures of drugs to enhance their properties and effectiveness.
Used in Agrochemical Production:
2,2,2-Trifluoro-1-(4-methoxy-3-methyl-phenyl)-ethanol is also utilized in the manufacturing of agrochemicals, where its chemical properties can be leveraged to develop new and improved products for agricultural applications.
Used in Chemical Manufacturing:
2,2,2-Trifluoro-1-(4-methoxy-3-methyl-phenyl)-ethanol is employed as a solvent or intermediate in the manufacturing of other chemical compounds, indicating its versatility in the chemical industry.
Safety and Storage:
Due to its chemical nature, 2,2,2-Trifluoro-1-(4-methoxy-3-methyl-phenyl)-ethanol should be handled with care and stored in a cool, dry place away from heat and direct sunlight to ensure its stability and prevent potential hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 343777-46-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,3,7,7 and 7 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 343777-46:
(8*3)+(7*4)+(6*3)+(5*7)+(4*7)+(3*7)+(2*4)+(1*6)=168
168 % 10 = 8
So 343777-46-8 is a valid CAS Registry Number.
343777-46-8Relevant academic research and scientific papers
The reduction of aryl trifluoromethyl ketones by sodium borohydride. The hydride transfer process
Stewart, Ross,Teo, K. C.
, p. 2491 - 2496 (2007/10/02)
The rates of reduction of 17 aryl trifluoromethyl ketones by sodium borohydride in 2-propanol have been measured.The rho (ρ) value is 3.12, excluding the 4-amino and 4-dimethylamino groups, which both lower the rate to a greater extent than their ? values predict.The close correspondence between substituent effects for hydride addition in the methyl and trifluoromethyl series (excluding the amino groups) suggests that normal substituent effects are to be expected for oxidation processes involving hydride removal in trifluoromethyl compounds.The present results are consistent with the oxidation of aryl trifluoromethyl carbi ols by permanganate taking place by hydrogen atom abstraction.The effect of substituents on the rate of reduction of the trifluoromethyl ketones is almost identical to that on the equilibrium constant for formation of the ketone hydrates.The application of the reactivity-selectivity principle to the reduction reaction is also considered.Reduction of the 4-ethyl compound has ΔH = 2.7 kcal mol-1 and ΔS = -38 cal deg-1 mol-1.
