343798-57-2Relevant academic research and scientific papers
TfOH-Promoted Reaction of 2,4-Diaryl-1,1,1-Trifluorobut-3-yn-2-oles with Arenes: Synthesis of 1,3-diaryl-1-CF3-indenes and versatility of the reaction mechanisms
Zerov, Aleksey V.,Kazakova, Anna N.,Boyarskaya, Irina A.,Panikorovskii, Taras L.,Suslonov, Vitalii V.,Khoroshilova, Olesya V.,Vasilyev, Aleksander V.
supporting information, (2018/11/30)
The TfOH-mediated reactions of 2,4-diaryl-1,1,1-trifluorobut-3-yn-2-oles (CF3-substituted diaryl propargyl alcohols) with arenes in CH2Cl2 afford 1,3-diaryl-1-CF3-indenes in yields up to 84%. This new process for synthesis of such CF3-indenes is complete
Pd-catalyzed selective carbonylative and non-carbonylative couplings of propiolic acid: One-pot synthesis of diarylalkynones
Kim, Wonyoung,Park, Kyungho,Park, Ahbyeol,Choe, Juseok,Lee, Sunwoo
supporting information, p. 1654 - 1657 (2013/06/26)
Diarylalkynones were synthesized from one-pot Pd-catalyzed carbonylative and noncarbonylative coupling reactions of propiolic acid with aryl iodides under a carbon monoxide atmosphere. Aryl iodide (2.0 equiv), propiolic acid (1.0 equiv), Pd(PPh3)2Cl2 (5 mol %), CuCl (10 mol %), Et3N (6.0 equiv), and CO (8 atm) were reacted under optimized conditions in CH3CN at 80 °C for 1 h. This process afforded good yields and functional group tolerance.
Oxidation of aromatic compounds: VII oxidation of symmetrically substituted 1,3-diarylpropynones in the system CF3COOH-CH2Cl2-PbO2. New synthesis method of 1,1,2,2-tetraaroylethenes
Vasil'ev,Rudenko,Grinenko
, p. 1157 - 1162 (2007/10/03)
Preparative oxidation of 1,3-diarypropynones ArC≡CCOAr in a system CF3COOH-CH2Cl2-PbO2 at 18-20°C within 1.5-25 h results in 1,1,2,2-tetraaroylethenes (ArCO)2C= C(COAr)2 in yields up to 75%. The most easily and efficiently the products form from the substrates where the aryl moiety conjugated with the triple bond contains electron-donating substituents p-MeO, p-Me, and p-t-Bu. On heating with hydrazine 1,1,2,2-tetrakis(4-methoxyphenylcarbonyl)ethene is converted into heterocyclic structures: pyridazine and 2,3,6,7-tetraazanaphthalene derivatives.
