34390-89-1Relevant academic research and scientific papers
Synthesis and antituberculosis activity of new fatty acid amides
D'Oca, Caroline Da Ros Montes,Coelho, Tatiane,Marinho, Tamara Germani,Hack, Carolina Rosa Lopes,Da Costa Duarte, Rodrigo,Da Silva, Pedro Almeida,D'Oca, Marcelo Gonalves Montes
scheme or table, p. 5255 - 5257 (2010/10/03)
This work reports the synthesis of new fatty acid amides from C16:0, 18:0, 18:1, 18:1 (OH), and 18:2 fatty acids families with cyclic and acyclic amines and demonstrate for the first time the activity of these compounds as antituberculosis agents against Mycobacterium tuberculosis H37Rv, M. tuberculosis rifampicin resistance (ATCC 35338), and M. tuberculosis isoniazid resistance (ATCC 35822). The fatty acid amides derivate from ricinoleic acid were the most potent one among a series of tested compounds, with a MIC 6.25 μg/mL for resistance strains.
A NEW CHIRAL RECOGNITION IN AMINOLYSIS OF 3-ACYL-4(R)-METHOXYCARBONYL-1,3-THIAZOLIDINE-2-THIONE WITH RACEMIC AMINES
Nagao, Yoshimitsu,Yagi, Masahiro,Ikede, Takao,Fujita, Eiichi
, p. 201 - 204 (2007/10/02)
A chiral recognition was observed in aminolysis of 3-acyl-4(R)-methoxycarbonyl-1,3-thiazolidine-2-thione 1 by racemic amine 2 to give an optically active amide (S-excess) and amine (R-excess).
