343944-48-9Relevant academic research and scientific papers
Some reactions with p-ethoxyphenylcyano-thioforamide: Synthesis of pyrrole, pyrrolo[2,3-c]pyrrole, imidazo[4,5-b]quinoxalines and hydantoin derivatives
Ammar,El-Sharief,Ali,Mohamed,Mohamed
, p. 173 - 185 (2000)
P-Ethoxyphenylcyanothioformamide (1) was reacted with αβ-unsaturated ketone (2) and N-p-chlorophenylmaleimide (4) to furnish pyrrole and pyrrolo[2,3-c]pyrrol-4,6-diones (3) and (5) respectively. Also, interaction of 1 with anthranilic acid and o-phenylenediamine produced 3-(4′-ethoxyphenyl)-2-thioxoquinazolin-4-one (6) and 2-thioxobenzimidazoles (7). When, 1 was reacted with iso(thio)cyanates caused cyclization to afford 5-imino-4-thioxoimidazolidinones (9). Compound 9 was subjected to some reagents such as hydrazine hydrate, thiosemicarbazide, o-phenylenediamines, hydrogen sulfide and HCl to give 5-hydrazono, 4-thiosemicarbazono, and thiohydantoin derivatives (10-17), respectively.
