343953-27-5Relevant academic research and scientific papers
A new, highly stereoselective synthesis of β-unsubstituted (Z)-γ-alkylidene-butenolides using bromine as a removable stereocontrol element
Boukouvalas, John,Beltrán, Paola P.,Lachance, Nicolas,C?té, Sébastien,Maltais, Fran?ois,Pouliot, Martin
, p. 219 - 222 (2007/10/03)
Several β-unsubstituted (Z)-γ-alkylidenebutenolides have been prepared in highly stereocontrolled fashion by implementing a steric directing group stratagem in the vinylogous aldol condensation of butenolides with aldehydes. Applications to the synthesis of the antitumor heptene (S)-melodorinol and a thiophenelactone from Chamaemelum nobile L. are described. Georg Thieme Verlag Stuttgart.
SYNTHESIS OF 4-YLIDENEBUTENOLIDES FROM 2-TRIMETHYLSILOXYFURAN
Asaoka, Morio,Yanagida, Noboru,Ishibashi, Keiji,Takei, Hisashi
, p. 4269 - 4270 (2007/10/02)
Dehydration or dealkoxylation of the reaction products of various aldehydes, ketones, and acetals with 2-trimethylsiloxyfuran gave corresponding 4-ylidenebutenolides in good to high overall yields.
