344-65-0

Basic information

• Product Name: 2-Bromo-5-chlorobenzotrifluoride
• Synonyms: Benzene,2-bromo-5-chloro-1-(trifluoromethyl)-;2-bromo-5-chloro-α,α,α-trifluorotoluene;2-Bromo-5-chlorobenzotrifluoride 99%;2-Bromo-5-chlorobenzotrifluoride99%;2-BROMO-5-CHLOROBENZOTRIFLUORIDE, 98+%;1-Bromo-4-chloro-2-(trifluoromethyl)benzene;2-BROMO-5-C;2-Bromo-5-chorobenzotrifluoride
• CAS NO: 344-65-0
• Molecular Formula: C₇H₃BrClF₃
• Molecular Weight: 259.45
• EINECS: -0
• Product Categories: Bromine Compounds;Chlorine Compounds;Fluorine Compounds
• Mol File: 344-65-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: 18-20°C
• Boiling Point: 179-180 °C(lit.)
• Flash Point: 198°C
• Appearance: Clear colourless to slightly yellow liquid
• Density: 1.759 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.779mmHg at 25°C
• Refractive Index: n20/D 1.5080(lit.)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• BRN: 2448030
• CAS DataBase Reference: 2-Bromo-5-chlorobenzotrifluoride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-5-chlorobenzotrifluoride(344-65-0)
• EPA Substance Registry System: 2-Bromo-5-chlorobenzotrifluoride(344-65-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39-36-37-23
• WGK Germany: 3
• Hazardous Substances Data: 344-65-0(Hazardous Substances Data)

Usage

Chemical Properties

Clear colourless to slightly yellow liquid

Uses

2-Bromo-5-chlorobenzotrifluoride was used in preparation of 6-[4-chloro-2-(trifluoromethyl)phenyl]-3-fluoro-2-methylpyridine and 4,4′-dichloro-2,2′-bis(trifluoromethyl) diphenyl sulphone.

InChI:InChI=1/C7H3BrClF3/c8-6-2-1-4(9)3-5(6)7(10,11)12/h1-3H

Upstream product

• 98-15-7 3-chlorotrifluoromethylbenzene 
• 393-36-2 4-bromo-3-(trifluoromethyl)aniline 
• 351-36-0 N-acetyl-3-trifluoromethylbenzenamine 
• 98-16-8 3-trifluoromethylaniline 

Downstream Products

• 154521-75-2 4,4'-dichloro-2,2'-bis(trifluoromethyl)diphenyl sulphoxide 
• 1636166-30-7 methyl-6-(4-chloro-2-(trifluoro methyl)phenyl)-2-methyl pyrimidine-4-carboxylate 
• 1198180-53-8 ({(3S)-1-[4-chloro-2-(trifluoromethyl)phenyl]pyrrolidin-3-yl}oxy)acetic acid 
• 1198181-39-3 (3S)-1-[4-chloro-2-(trifluoromethyl)phenyl]pyrrolidin-3-ol 
• 154521-76-3 4,4'-dichloro-2,2'-bis(trifluoromethyl)diphenyl sulphone 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF SUBSTITUTED BENZOTRIHALIDE

The present invention provides a process for the preparation of compound of Formula I; wherein X is selected from the group consisting of fluorine, chlorine, bromine and iodine; Y is selected from X and -NR1R2; R1 and R1, independent of each other, are selected from the group consisting of hydrogen, C1-4 alkyl and –COR; R is C1-4 alkyl.