3440-53-7

Basic information

• Product Name: 4(1H)-Quinazolinethione, 2-[2-(4-nitrophenyl)ethenyl]-
• CAS NO: 3440-53-7
• Molecular Formula: C16H11N3O2S
• Molecular Weight: 309.348
• Mol File: 3440-53-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4(1H)-Quinazolinethione, 2-[2-(4-nitrophenyl)ethenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(1H)-Quinazolinethione, 2-[2-(4-nitrophenyl)ethenyl]-(3440-53-7)
• EPA Substance Registry System: 4(1H)-Quinazolinethione, 2-[2-(4-nitrophenyl)ethenyl]-(3440-53-7)

Safety Data

• Hazardous Substances Data: 3440-53-7(Hazardous Substances Data)

Upstream product

• 6484-24-8 2-methyl-4-chloroquinazoline 

Relevant articles and documents

Studies on quinazolines. Part I. Annelation to the quinazoline ring utilizing amino acid esters

The reaction of quinazoline-4(3H)-thiones 2a-d with amino acid ester hydrochlorides in boiling solvents, under the basic catalysis, afforded the corresponding substitution products (3-6)a-e in low yield. The reaction could be improved by carrying it without a solvent yielding imidazo[1,2-c]- and pyrimido[1,2-c]quinazolines (7-10)a-e. The antibacterial and antifungal activities of the prepared compounds were tested.