344262-76-6Relevant academic research and scientific papers
Structure based designing of triazolopyrimidone-based reversible inhibitors for kinases involved in NSCLC
Singh, Pankaj Kumar,Chaudhari, Dasharath,Jain, Sanyog,Silakari, Om
, p. 1565 - 1571 (2019)
Secondary acquired mutant EGFR (L858R-T790M)overexpressed NSCLC forms one of the prevalent form of resistant NSCLC. Another subset of resistant NSCLC includes amplified cMET in mutant EGFR derived tumours. Thus, in continuation to our previous work on the
