344295-54-1

Basic information

• Product Name: <α-2H>benzyl methyl sulfone
• CAS NO: 344295-54-1
• Molecular Weight: 171.224
• Mol File: 344295-54-1.mol

Chemical Properties

• CAS DataBase Reference: <α-2H>benzyl methyl sulfone(CAS DataBase Reference)
• NIST Chemistry Reference: <α-2H>benzyl methyl sulfone(344295-54-1)
• EPA Substance Registry System: <α-2H>benzyl methyl sulfone(344295-54-1)

Safety Data

• Hazardous Substances Data: 344295-54-1(Hazardous Substances Data)

Upstream product

• 344246-80-6 <α-2H>benzyl methyl thioether 
• 14090-81-4 S-(-)-benzylmethylsulfoxide 
• 29293-45-6 C₈H₉⁽²⁾HOS 

Relevant articles and documents

Stereochemistry of the α-Sulfinyl Phenylmethyl Carboanion. Reevaluation of the Configuration

Methyl phenylmethyl sulfoxide and tert-butyl phenylmethyl sulfoxide were subjected to H-D exchange and methylation in tetrahydrofuran and water or methanol.The stereochemistry of electrophile attack depends on the reaction conditions and on the electrophi

Preparation of Chiral 1-Deuteriobenzenemethanethiols by Using α',β Elimination of Carbanions Derived from Benzylic Thioethers

The α',β elimination of the carbanion derived from benzyl isolongifolyl thioether and benzyl camphyl thioether gives the chiral benzyl mercaptan, the S isomer with 38 +/- 6percent ee and the R isomer with 49 +/- 7percent ee.The chirality of the benzyl mercaptan was determined by optical rotation of benzyl methyl thioether and thiosulfone.The enantiomeric excess was evaluated from 1H NMR measurement of ethyl (benzylthio)phenylacetate prepared from (-)-mandelic acid.The enantiomeric excess at carbon C-2 of ethyl (benzylthio)phenylacetate wasdetermined with the chiral europium chelate and was about 60percent.These results are discussed with reference to the transition state of the α,β elimination and to related processes.