3443-83-2

Usage

Uses

Used in Pharmaceutical Industry:
Tetradecanoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester is used as a therapeutic agent for its ability to slow the plasma clearance and decrease the liver uptake of remnants derived from injected chylomicrons and chylomicron-like emulsions in rats. This property makes it a valuable compound for the development of treatments targeting lipid metabolism and related conditions.
Used in Nutritional Applications:
In the field of nutrition, Tetradecanoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester can be utilized as an ingredient in the development of supplements or functional foods aimed at improving lipid metabolism and overall health.
Used in Cosmetics Industry:
Due to its lipid nature, Tetradecanoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester may also find applications in the cosmetics industry as an ingredient in skincare products, potentially offering moisturizing and protective benefits to the skin.
Used in Research:
Tetradecanoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester can be employed as a research tool in the study of lipid metabolism, cell signaling, and other biological processes involving monoacylglycerols. Its unique structure may provide insights into the mechanisms of various cellular functions and contribute to the development of new therapeutic strategies.

Upstream product

• 124-10-7 methyl myristoate 
• 56-81-5 glycerol 
• 544-63-8 n-tetradecanoic acid 

Relevant academic research and scientific papers

Design of well balanced hydrophilic-lipophilic catalytic surfaces for the direct and selective monoesterification of various polyols

The transesterification process is a well known reaction of organic chemistry. However, the monoesterification of unprotected polyols such as glycerol or sucrose is much more complex and the design of selective catalysts is becoming a huge challenge in order to avoid many protection and deprotection steps, harmful for the cost and the environmental impact of the resulting process. In this study, we showed that the control of the hydrophilic-lipophilic balance of heterogeneous catalysts is a crucial key in order to tune both the catalyst activity and the monoester selectivity. Indeed, whereas homogeneous guanidine led to low selectivity toward monoesters, its anchorage on a hydrophilic solid support such as silica allowed us to prepare two basic hybrid organic-inorganic materials able to selectively afford monoesters in high yield and in an environmentally-friendly process, at low temperature and starting from an equimolecular mixture of unprotected polyols and various fatty methyl esters. The Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2005.

COSMETIC EMULSION PREPARATION AND AGENT FOR EXTERNAL USE

An emulsion which has an average particle diameter of 100 nm or smaller and comprises: (D) a polyglycerol/fatty acid ester which has an HLB of 13 or higher and in which the polyglycerol is one in which the average degree of polymerization is 8 to 12, the total content of the pentamer and hexamer is 50% by weight or higher, and the total content of the tetramer and lower polymers is less than 20% by weight, and the fatty acid residue is C14-22 hydrocarbon group; (E) a polyglycerol/fatty acid ester which has an HLB of 5 to 11 and in which the polyglycerol is one in which the average degree of polymerization is 2 to 12, the total content of the tetramer and lower polymers is 20% by weight or higher, each of (2/3)n components being contained in an amount of at least 5% by weight or more, where n (n is 2 or more) is taken to be an average degree of polymerization (when (2/3)n is not a natural number, (2/3)n is considered to be a lowest natural number greater than (2/3)n), and the fatty acid residue is a C14-22 hydrocarbon group; (F) a lecithin; and (G) an oily ingredient.