344346-72-1

Upstream product

• 495-69-2 Hippuric Acid 
• 104-88-1 4-chlorobenzaldehyde 
• 100-46-9 benzylamine 
• 15601-44-2 (Z)-2-phenyl-4-(4-chlorobenzylidene)-5(4H)-oxazolone 

Relevant academic research and scientific papers

2W10O32 catalyzed efficient one-pot pseudo-four component synthesis of AT-130 analogues under microwave irradiations

Di[1,6-bis(3-methylimidazolium-1-yl)hexane] decatangstate ([C 6(MIm)2]2W10O32) was found to be a novel, powerful and effective catalyst for the preparation of N-benzoylglycine carbamides as derivatives of AT-130 via one-pot multicomponent reaction performed under microwave irradiations. The products were obtained in high to excellent yields, thus providing a unique strategy to the large-scale synthesis of these compounds.

Reaction of benzonitrilium N-phenylimide with (Z)-4-arylmethyleneimidazol-5(4H)-ones

The title reaction, when carried out in chloroform in the presence of triethylamine, yields the spirocycloadducts 5 which upon treatment with a base affords 1,3,4,triaryl-5-pyrazolecarboxamides 12.