344357-17-1

Upstream product

• 29117-58-6 (2S,3S)-3-Methyl-pentane-1,2-diol 
• 104973-58-2 (2S,3S)-2-(acetyloxy)-3-methylpentanoic acid 
• 70639-22-4 (2S,3S)-1,2-Epoxy-3-methylpentane 
• 824-94-2 p-methoxybenzyl chloride 
• 344357-16-0 (2R,3S)-2-(2-hydroxy-3-methylpentyl)-1,3-dithiane 

Downstream Products

• 344357-18-2 (3R,4S)-3-(4-methoxybenzyloxy)-4-methylhexanal 
• 344357-32-0 (S)-3-[(3R,4S)-1-Hydroxy-3-(4-methoxy-benzyloxy)-4-methyl-hexyl]-3-methoxymethoxy-4-methyl-4-vinyl-dihydro-furan-2-one 
• 344357-26-2 (3R,4R,3'R,4'S)-3-[3'-(4-methoxybenzyloxy)-4'-methylhexanoyl]-3-methoxymethyloxy-4-methyl-4-vinyl-γ-butyrolactone 
• 344357-21-7 (3S,4R,3'R,4'S)-3-[3'-(4-methoxybenzyloxy)-4'-methylhexanoyl]-3-methoxymethyloxy-4-methyl-4-vinyl-γ-butyrolactone 

Relevant academic research and scientific papers

Synthesis of Hyperolactones A and C

Hyperolactones A (1) and C (3) have been synthesized starting from (S)-malic acid by a straightforward route. The unique spirolactone skeleton was efficiently constructed by one-pot reaction as a key step. The absolute stereochemistry of hyperolactones was unambiguously established by this synthesis.