34442-95-0

Basic information

• Product Name: N-(o-acetamidophenyl)phthalimide
• Synonyms: N-(o-acetamidophenyl)phthalimide
• CAS NO: 34442-95-0
• Molecular Weight: 280.283
• Mol File: 34442-95-0.mol

Chemical Properties

• CAS DataBase Reference: N-(o-acetamidophenyl)phthalimide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(o-acetamidophenyl)phthalimide(34442-95-0)
• EPA Substance Registry System: N-(o-acetamidophenyl)phthalimide(34442-95-0)

Safety Data

• Hazardous Substances Data: 34442-95-0(Hazardous Substances Data)

Upstream product

• 34442-94-9 N-(o-nitrophenyl)phthalimide 
• 85-44-9 phthalic anhydride 
• 34801-09-7 N-(2-aminophenyl)acetamide 
• 4506-62-1 N-(2-aminophenyl)phthalimide 
• 108-24-7 acetic anhydride 

Relevant articles and documents

Kinetic versus thermodynamic access to imidazoisoindolones, benzimidazoisoindolones, and [1,4]diazepinoisoindolones: Intramolecular nitrogen and π-aromatic trapping of N-acyliminium cation

Efficient assembly of substituted imidazo[2,1-a]isoindolones I is reported from suitable α,β-diamine IV (or corresponding β-nitroamine) and phthalic anhydride (1) in a three- or four-step sequence in good yields. The key step of this methodology is based on an intramolecular α-aza- amidoalkylation of the N-acyliminium species. Furthermore, when R2 is an aromatic moiety a competing α-amidoalkylation took place and imidazo[2,1-a]isoindolones (or benzimidazo[2,1-a]isoindolones) I and/or isoindolo[1,4]benzodiazepines III were obtained under kinetic or thermodynamic control. The chemoselectivity of these transformations is also discussed.