344452-36-4Relevant academic research and scientific papers
3-ethyl-, 3-propyl- or 3-butyl-chroman and thiochroman derivatives
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, (2008/06/13)
A compound having the following general formula (1): in whichR1 represents an ethyl group, etc.;R2 represents a hydrogen atom, etc.;R3 represents a C1-C5 perhalogenoalkyl group, etc.;each of R4 and R5 independently represents a hydrogen atom, etc.;X represents an oxygen atom or a sulfur atom;m represents an integer of 2 to 14; andn represents an integer of 2 to 7;or an enantiomer of the compound, or a hydrate or a pharmaceutically acceptable salt of the compound or its enantiomer is advantageous in pharmaceutical use because of its anti-estrogenic activity.
