344461-43-4Relevant academic research and scientific papers
First total synthesis of (-)-Circumdatin H, a novel mitochondrial NADH Oxidase inhibitor
Bose, D. Subhas,Chary, M. Venu
, p. 643 - 650 (2010)
An efficient and highly convergent synthesis of the mitochondrial NADH oxidase inhibitor (-)-circumdatin H is described. The strategy employs the intramolecular Eguchi aza-Wittig protocol as a key step to install the crucial central core BC ring system, leading to the first total synthesis of the target molecule. Georg Thieme Verlag Stuttgart · New York.
