3445-78-1

Usage

Uses

Used in Organic Synthesis:
Pyridino[5',6':2,3]trithione is used as a key intermediate in the synthesis of various organic compounds and materials. Its unique structural properties and reactivity enable the formation of a wide range of organic molecules, contributing to the development of new materials and chemical processes.
Used in Pharmaceutical Industry:
Pyridino[5',6':2,3]trithione is studied for its potential use in pharmaceuticals due to its interesting chemical properties. Its unique structure and reactivity make it a promising candidate for the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
Pyridino[5',6':2,3]trithione has also been studied for its potential use in agrochemicals. Its unique structural properties and reactivity can be harnessed to develop new agrochemical products, such as pesticides and herbicides, with improved efficacy and selectivity.

Upstream product

• 38521-46-9 3-carboxy-2-mercaptopyridine 
• 65282-42-0 1,2-dithiolo<5,4-b>pyridin-3-one 
• 27916-10-5 2,2'-dithiobis(3-pyridinecarboxylic acid) 
• 154344-45-3 2-phenethylisothiazolo<5,4-b>pyridin-3(2H)-one 
• 154344-33-9 2-phenylethylisothiazolo<5,4-b>pyridine-3(2H)-thione 
• 154344-46-4 2-(3-phenylpropyl)isothiazolo<5,4-b>pyridin-3(2H)-one 
• 154344-34-0 2-(3-phenylpropyl)isothiazolo<5,4-b>pyridine-3(2H)-thione 
• 91859-79-9 N-Benzyl-2-mercapto-nicotinamide 
• 154344-26-0 N-Benzyl-2-mercapto-thionicotinamide 
• 154344-25-9 N-Hexyl-2-mercapto-thionicotinamide 
• 154344-24-8 2-Mercapto-N-pentyl-thionicotinamide 
• 154344-23-7 N-Butyl-2-mercapto-thionicotinamide 
• 154344-22-6 2-Mercapto-N-propyl-thionicotinamide 
• 65282-47-5 2-butylisothiazolo<5,4-b>pyridin-3(2H)-one 

Downstream Products

• 65282-42-0 1,2-dithiolo<5,4-b>pyridin-3-one 
• 154344-26-0 N-Benzyl-2-mercapto-thionicotinamide 
• 154344-28-2 2-Mercapto-N-(3-phenyl-propyl)-thionicotinamide 
• 154344-32-8 2-benzylisothiazolo<5,4-b>pyridine-3(2H)-thione 
• 154344-33-9 2-phenylethylisothiazolo<5,4-b>pyridine-3(2H)-thione 
• 154344-27-1 2-Mercapto-N-phenethyl-thionicotinamide 
• 91859-79-9 N-Benzyl-2-mercapto-nicotinamide 
• 330667-58-8 2-mercapto-N-phenethyl-nicotinamide 
• 330667-59-9 2-mercapto-N-(3-phenyl-propyl)-nicotinamide 
• 65282-46-4 2-(p-chlorobenzyl)isothiazolo<5,4-b>pyridin-3-one 
• 65282-54-4 N-(p-chlorobenzyl)-2-mercaptonicotinamide 

Relevant academic research and scientific papers

1,2-Dithiolan-3-ones and derivatives structurally related to leinamycin. Synthesis and biological evaluation

Leinamycin, an antitumor antibiotic isolated from Streptomyces sp., shows a 1,2-dithiolan-3-one 1-oxide heterocycle that appears to be involved in the biological activity. Several derivatives related to 1,2-dithiolan-3-one 1-oxide have been prepared and their activity as antineoplastic agents have been investigated. The synthesized compounds did not display a significative antitumor or cytotoxic activity in vitro.

3H-[1,2]Dithiolo[3,4-b]pyridine-3-thione and its derivatives. Synthesis and antimicrobial activity

A series of 2-substituted isothiazolo[5,4-b]pyridine-3(2H)-thiones, isothiazolo[5,4-b]pyridin-3(2H)-ones, N-substituted 2-sulfanylnicotinamides and the corresponding carbothioamide derivatives were synthesized and evaluated for their antimicrobial activity against several strains of Gram+ and Gram-bacteria and fungi. Chemical syntheses were resumed into a comprehensive cyclic route that enables the reversible conversion for each derivative of the series considered. Among the tested compounds the N-(aralkyl)-2-sulfanylnicotinamides show the highest fungitoxicity (MIC=1.25-5 μg/ml). The best activity towards Gram-positive bacteria was in the range of 2.5-5 μg/ml. Activity against Gram-negative bacteria was generally very poor for all compounds. Copyright

Synthesis of 2-Substituted Isothiazolopyridin-3-ones

The synthesis of some 2-substituted derivatives 1-4 of all four isomeric isothiazolopyridin-3-ones is described.Several novel 1,2-dithiolopyridin-3-ones and 3-thiones were prepared as intermediates.