344796-32-3

Upstream product

• 99493-12-6 B-crotyldiisopinocampheylborane 
• 344796-28-7 (2R,3S,4S)-3-(tert-Butyl-dimethyl-silanyloxy)-4-(4-methoxy-benzyloxy)-2-methyl-pentanal 

Downstream Products

• 344796-38-9 1-[(1S,2S,3S,4R,5R)-2-(tert-Butyl-dimethyl-silanyloxy)-1,3,5-trimethyl-4-triethylsilanyloxy-hept-6-enyloxymethyl]-4-methoxy-benzene 

Relevant academic research and scientific papers

An improved procedure for the separation of (+) or (-)-isopinocampheol, the major side product of the oxidation workup procedure of Brown's asymmetric crotylborations

Separation of (+) or (-)-isopinocampheol, the major side product of the oxidation workup procedure of Brown's asymmetric reactions such as crotylborations from the desired product is quite tedious and often requires repeated column chromatography. It is discovered that a sublimation process can be used to easily separate this major side product.

Synthetic studies of antitumor natural products superstolides A and B. Construction of C20-C26 fragment of superstolide A.

[structure: see text] The C20-C26 portion of the antitumor macrolide superstolide A was synthesized by employing Brown's asymmetric crotylboronate methodology.