344797-51-9

Basic information

• Product Name: (1'R)-(-)-1-(2'-hydroxy-1'-phenyl-ethyl)-3,4-dihydro-(1H)-pyridin-2-one
• Synonyms: (1'R)-(-)-1-(2'-hydroxy-1'-phenyl-ethyl)-3,4-dihydro-(1H)-pyridin-2-one
• CAS NO: 344797-51-9
• Molecular Weight: 217.268
• Mol File: 344797-51-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1'R)-(-)-1-(2'-hydroxy-1'-phenyl-ethyl)-3,4-dihydro-(1H)-pyridin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (1'R)-(-)-1-(2'-hydroxy-1'-phenyl-ethyl)-3,4-dihydro-(1H)-pyridin-2-one(344797-51-9)
• EPA Substance Registry System: (1'R)-(-)-1-(2'-hydroxy-1'-phenyl-ethyl)-3,4-dihydro-(1H)-pyridin-2-one(344797-51-9)

Safety Data

• Hazardous Substances Data: 344797-51-9(Hazardous Substances Data)

Upstream product

• 211919-57-2 (1'R)-(-)-1-(2'-hydroxy-1'-phenyl-ethyl)-(1H)-pyridin-2-one 

Downstream Products

• 156873-53-9 (1'R,6S)-(+)-1-(2'-hydroxy-1'-phenyl-ethyl)-6-propyl-piperidin-2-one 
• 88056-96-6 (2R,2'S)-(+)-2-phenyl-2-(2'-propyl-piperidin-1'-yl)-ethanol 
• 555-92-0 (S)-coniine hydrochloride 
• 374890-30-9 (3R,8S,8aS)-8-Hydroxy-3-phenyl-hexahydro-oxazolo[3,2-a]pyridin-5-one 
• 152555-02-7 (3R,8aR)-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine 

Relevant articles and documents

New methodology for the synthesis of enantiopure (3R,2aR)-(-)-3-phenyl-hexahydro-oxazolo[3,2-a]-pyridin-5-one: A synthesis of (S)-(+)-coniine

A new and efficient methodology for the enantiopure synthesis of (3R,2aR)-(-)-3-phenyl-hexahydro-oxazolo[3,2-a]pyridin-5-one 3 starting from (1′R)-(-)-1-(2′-hydroxy-1′-phenyl-ethyl)-(1H)-pyridin-2-one 1 is described. In addition, the enantiospecific synthesis of (S)-(+)-coniine hydrochloride 6 in good yield from 3 is reported.