3448-12-2 Usage
Uses
Used in Pharmaceutical Industry:
(1,1-DIOXIDOTETRAHYDROTHIEN-3-YL)HYDRAZINE is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure, featuring a thienyl ring and a dioxido substituent, may contribute to the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, (1,1-DIOXIDOTETRAHYDROTHIEN-3-YL)HYDRAZINE may serve as a building block for the creation of novel agrochemicals. Its potential role in this industry could be attributed to its ability to form complexes with other molecules, which might enhance the effectiveness of pesticides or other agricultural chemicals.
Used in Materials Science:
(1,1-DIOXIDOTETRAHYDROTHIEN-3-YL)HYDRAZINE could be utilized in materials science for the development of new materials with unique properties. Its hydrazine derivative nature and the presence of a thienyl ring might allow for the engineering of materials with specific characteristics, such as improved conductivity or enhanced stability, depending on the application.
Check Digit Verification of cas no
The CAS Registry Mumber 3448-12-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,4 and 8 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 3448-12:
(6*3)+(5*4)+(4*4)+(3*8)+(2*1)+(1*2)=82
82 % 10 = 2
So 3448-12-2 is a valid CAS Registry Number.
InChI:InChI=1/C4H12N2O2S/c5-6-4-1-2-9(7,8)3-4/h4H,1-3,6H2,5H3/q+2/t4-/m1/s1
3448-12-2Relevant academic research and scientific papers
Discovery, synthesis and characterization of a series of (1-alkyl-3-methyl-1H-pyrazol-5-yl)-2-(5-aryl-2H-tetrazol-2-yl)acetamides as novel GIRK1/2 potassium channel activators
Sharma, Swagat,Kozek, Krystian A.,Abney, Kristopher K.,Kumar, Sushil,Gautam, Nagsen,Alnouti, Yazen,David Weaver,Hopkins, Corey R.
, p. 791 - 796 (2019/02/06)
The present study describes the discovery and characterization of a series of 5-aryl-2H-tetrazol-3-ylacetamides as G protein-gated inwardly-rectifying potassium (GIRK) channels activators. Working from an initial hit discovered during a high-throughput screening campaign, we identified a tetrazole scaffold that shifts away from the previously reported urea-based scaffolds while remaining effective GIRK1/2 channel activators. In addition, we evaluated the compounds in Tier 1 DMPK assays and have identified a (3-methyl-1H-pyrazol-1-yl)tetrahydrothiophene-1,1-dioxide head group that imparts interesting and unexpected microsomal stability compared to previously-reported pyrazole head groups.
