344864-87-5Relevant academic research and scientific papers
Electroorganic Chemistry. 82. β-Amino Acid Esters from α-Methoxycarbamates and Ketene Silyl Acetals; Cyclization to β-Lactams
Shono, Tatsuya,Tsubata, Kenji,Okinaga, Nobuyuki
, p. 1056 - 1059 (2007/10/02)
A new synthetic method of β-lactams 1'is described.The key intermediates, N-carbomethoxy-β-amino acid esters 2', were synthesized by the reaction of α-methoxylated carbamates 3' with ketene methyl trimethylsilyl acetals 4' catalyzed by titanium tetrachlor
