344866-89-3Relevant academic research and scientific papers
Epoxymethylation of 2-Acyl-Substituted NH Heterocycles and Transformations of the Epoxymethylation Products
Kharaneko, A. O.,Kharaneko, O. I.,Pekhtereva, T. M.
, p. 1677 - 1684 (2020)
Abstract: A new procedure has been proposed for the synthesis of previously unknown pyrrolo- and indolo-1,4-epoxy[1,4]oxazepines by epoxymethylation of 2-benzoyl-1H-pyrrole and 2-benzoyl-1H-indoles with epichlorohydrin. Some transformations of the epoxyme
Synthesis and pharmacological properties of analogs of oxapadol, a new analgesic agent
Dostert,Langlois,Guerret,et al.
, p. 199 - 205 (2007/10/02)
A series of various heterocyclic compounds related to Oxapadol was prepared and evaluated for analgesic activity in mice. Some of them possessed significant analgesic effects; their structure activity relationships and chemistry are discussed. These compounds represent, in the authors' opinion, a unique series of analgesic agents.
