344873-93-4

Upstream product

• 100-46-9 benzylamine 
• 78999-58-3 1-benzyl-3-(2-ethoxycarbonyl)ethylidene-2,5-piperazinedione 
• 78999-46-9 ethyl 2-chloroacetylamino-4-ethoxycarbonyl-2-butenoate 
• 88521-39-5 (Z)-1-benzyl-3-<2-(ethoxycarbonyl)ethylidene>-2,5-piperazinedione 
• 88521-38-4 4-ethoxycarbonyl-(Z)-2-chloroacetylamino-2-butenoate 
• 5965-53-7 diethyl 2-ketoglutarate 
• 88521-40-8 1-benzyl-3-(3-hydroxypropylidene)-2,5-piperazinedione 
• 78999-47-0 1-benzyl-3-(3-hydroxy)propylidene-2,5-piperazinedione 

Downstream Products

• 88521-55-5 9-Benzyl-6-methyl-1-oxa-6,9-diaza-spiro[4.5]decane-7,8,10-trione 
• 88521-52-2 4'-benzyl-spiro-3',5',6'-trione 
• 88521-49-7 4'-benzyl-1'-methylspiro-3',6'-dione 
• 88521-58-8 1-benzyl-3-(3-hydroxypropyl)-2,5-piperazinedione 
• 78999-51-6 spiro 

Relevant academic research and scientific papers

OXOLANE-2,2 prime -PIPERAZINE.

The compound 3-(3-hydroxy)propylidene-piperazine-2,5-dione, derived from ethyl 4-ethoxycarbonyl-2-chloroacetylamino-2-butenoate, was treated with N-bromosuccinimide (NBS) in chloroform to give the spiro- left bracket oxolane-2,2 prime -piperazine right br

FACILE SYNTHESES OF 3-SPIRO- AND 3,6-BRIDGED 2,5-PIPERAZINEDIONES

The intramolecular addition of hydroxyl group of 3-(3-hydroxyl)propylidene-2,5-piperazinedione to 3-position and the same substitution of 3-(3-hydroxy)propyl derivative to 6-position gave the corresponding 3-spiro- and 3,6-bridged 2,5-piperazinediones, re