344907-95-5

Basic information

• Product Name: 2-Butenoic acid, 4-oxo-2-[(1E)-2-phenylethenyl]-, ethyl ester, (2E)-
• CAS NO: 344907-95-5
• Molecular Formula: C14H14O3
• Molecular Weight: 230.263
• Mol File: 344907-95-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Butenoic acid, 4-oxo-2-[(1E)-2-phenylethenyl]-, ethyl ester, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butenoic acid, 4-oxo-2-[(1E)-2-phenylethenyl]-, ethyl ester, (2E)-(344907-95-5)
• EPA Substance Registry System: 2-Butenoic acid, 4-oxo-2-[(1E)-2-phenylethenyl]-, ethyl ester, (2E)-(344907-95-5)

Safety Data

• Hazardous Substances Data: 344907-95-5(Hazardous Substances Data)

Upstream product

• 66680-87-3 (E)-1-phenyl-(2-tributylstannyl)ethene 
• 260353-31-9 ethyl (Z)-2-bromo-4-hydroxy-2-butenoate 

Downstream Products

• 461641-20-3 (1S,2R)-(-)-cis-1-[(2R)-4-hydroxymethyl-2-phenyl-1,2,5,6-tetrahydropyridin-1-yl]-7-isopropylindan-2-ol 
• 461641-19-0 (1S,2R)-(-)-cis-1-[(2R)-4-hydroxymethyl-2-phenyl-1,2,5,6-tetrahydropyridin-1-yl]-7-methylindan-2-ol 
• 461641-05-4 (1S,2R)-1-((S)-4-Hydroxymethyl-6-phenyl-3,6-dihydro-2H-pyridin-1-yl)-indan-2-ol 
• 461641-15-6 5-isopropyl-4-phenyl-1,9,9a,10a-tetrahydro-4H,4bH-10-oxa-4a-aza-indeno[1,2-a]indene-2-carboxylic acid ethyl ester 
• 461641-11-2 5-methyl-4-phenyl-1,9,9a,10a-tetrahydro-4H,4bH-10-oxa-4a-aza-indeno[1,2-a]indene-2-carboxylic acid ethyl ester 

Relevant articles and documents

Significant acceleration of 6π-azaelectrocyclization resulting from a remarkable substituent effect and formal synthesis of the ocular age pigment A2-E by a new method for substituted pyridine synthesis

The remarkable acceleration of 6π-azaelectrocyclization due to the combination of the C4-carbonyl and the C6-alkenyl or phenyl substituents in 1-azatrienes was found. This observation was rationalized by considering the remarkable orbital interaction between the HOMO and LUMO of 1-azatrienes, which were obtained by molecular orbital calculations. The formal synthesis of the unusual retinal metabolite, A2-E, was achieved by two types of the new one-pot synthesis of substituted pyridines by utilizing the obtained facile 6π-azaelectrocyclization, one of which is compatible with the proposed metabolic pathway of A2-E.