344928-74-1

Usage

Uses

Used in Chemical Synthesis:
1,3,3-trimethyl-2-methylene-2,3-dihydro-1H-benzo[e]indole is used as a reagent in the preparation of stable and fluorescent switching spirooxazines. Its unique structure allows for the creation of these spirooxazines, which are valuable for their potential applications in various fields, such as materials science and molecular biology.
Used in Materials Science:
In the field of materials science, 1,3,3-trimethyl-2-methylene-2,3-dihydro-1H-benzo[e]indole is utilized for the development of advanced materials with specific properties. Its incorporation into the molecular structure of these materials can lead to enhanced stability, fluorescence, and other desirable characteristics.
Used in Molecular Biology:
1,3,3-trimethyl-2-methylene-2,3-dihydro-1H-benzo[e]indole also finds use in molecular biology, where it can be employed as a fluorescent probe or tag for studying biological processes and interactions. Its unique fluorescent properties make it a valuable tool for researchers in this field.
Overall, 1,3,3-trimethyl-2-methylene-2,3-dihydro-1H-benzo[e]indole is a versatile compound with a range of applications across different industries, from chemical synthesis to materials science and molecular biology. Its unique structure and properties make it a promising candidate for further research and development.

Upstream product

• 74-88-4 methyl iodide 
• 41532-84-7 2,3,3-trimethylbenzo[e]indole 
• 58464-25-8 1,1,2,3-tetramethyl-1H-benz[e]indol-3-ium iodide 

Downstream Products

• 123088-61-9 (1,1,3-trimethyl-1,3-dihydro-benz[e]indol-2-yliden)-acetaldehyde 

Relevant academic research and scientific papers

An efficient multiple-mode molecular logic system for pH, solvent polarity, and Hg2+ ions

A novel fluorophore 1,3-bis(1,1,3-trimethyl-1H-benzo[e]indol-2(3H)-ylidene)propan-2-one (L) was synthesized and fully characterized by 1H NMR, 13C NMR, HRMS, and X-ray single-crystal structural analysis. Compound L is a pH-controlled molecular switch due to its protonation. The fluorescence change in protic polar solvents means that this compound also could be used as a protic solvent polarity sensor. Among the considered metal ions, the fluorescence of compound L could be quenched completely by Hg2+ ions with a high selectivity. Based on these fluorescence characters, this fluorescent dye L has promising applications as a multiple-mode molecular logic system.

Synthesis method of Cy series fluorescein and application in DNA sequencing

The invention discloses a synthesis method of Cy series fluorescein and application in DNA sequencing. The method comprises: step A, enabling a reactant A (the formula is shown in the specification) to be refluxed with a reactant YCH2(CH2)4COOH or YR to obtain reaction intermediates B (the formula is shown in the specification) and C (the formula is shown in the specification); step B, enabling B(the formula is shown in the specification) obtained in the step A to react with D (the formula is shown in the specification) to obtain E (the formula is shown in the specification), then directly adding C (the formula is shown in the specification) to obtain a target product by a one-pot method; in each structural formula, Y is Cl, Br, I; R is Me, ethyl, propyl; X is O, CH (CH3)2; R1 to R4 are optionally H or SO3, or R1, R2 and a benzene ring jointly form a naphthalene ring and a derivative, or R3, R4 and a benzene ring jointly form a naphthalene ring and a derivative; n is 1, 3, 5. The method obtains the desired asymmetric structure fluorescein by the one-pot method, which has good reaction selectivity and is easy to separate and purify, in addition, required experimental conditionsare simple. The synthesis process is a conventional chemical reaction, and can be used for large-scale popularization.

SPIRO[CHROMAN-2,2'-INDOLE] DERIVATIVES AS CYANIDE ION CHEMOSENSORS

The invention describes new spiro[chroman-2,2'-indole] derivatives of formula (I). When compounds of the invention, 1',3',3,4-tetrahydrospiro[chromen-2,2'-indoles], are treated with solution containing cyanide ions, 3,4-dihydropyrane ring opening occurs,

Facile synthesis of spiro[benzo[e]indole-2,2′-piperidine] derivatives and their transformation to novel fluorescent scaffolds

The reaction of azaheterocyclic enamines with acrylamide was employed for the preparation of novel fluorescent scaffolds possessing a benzo[e]indoline moiety. Reaction of 3-substituted 2-methylidene-1H-benzo[e]indole with acrylamide gave rise to spiro[ben

Photochromic dye

The invention provides a photochromic dye of a structure containing a common structure of spirooxazine series compounds and three substituents. The photochromic dye according to the invention exhibits characteristics of a high heat stability, good light fatigue resistance, high sensitivity, extremely degradation rate and the like. This photochromic dye can be formulated with suitable organic solvents and used as photochromic functional colorants under UV light excitation. Further, this photochromic dye can be synthesized and purified in simple steps with cheap raw materials and hence at a greatly lowered production cost.