344948-00-1

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 344947-99-5 (R)-1-((3aR,5S,6S,6aR)-2,2-Dimethyl-6-[1,2,3]triazol-1-yl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-ethane-1,2-diol 
• 344947-95-1 1-[(3aR,5S,6S,6aR)-5-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl]-4-trimethylsilanyl-1H-[1,2,3]triazole 
• 344947-98-4 (R)-1-[(3aR,5S,6S,6aR)-2,2-Dimethyl-6-(4-trimethylsilanyl-[1,2,3]triazol-1-yl)-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl]-ethane-1,2-diol 
• 344947-97-3 1-[(3aR,5S,6S,6aR)-5-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl]-1H-[1,2,3]triazole 
• 22169-71-7 (R)-1-((3aR,5S,6S,6aR)-6-azido-2,2-dimethyltetrahydrofuro-[2,3-d][1,3]dioxol-5-yl)ethane-1,2-diol 
• 13964-23-3 3-azido-3-deoxy-1,2:5,6-di-(O-isopropylidene)-α-D-glucofuranose 

Downstream Products

• 344948-04-5 C₁₈H₂₁N₃O₄ 

Relevant academic research and scientific papers

Free-radical cyclizations onto differently substituted 1,2,3-triazoles installed in sugar templates

The synthesis and manipulation of differently substituted 1,2,3-triazoles (7-11 and 12-16) installed in sugar templates gave compounds 29-34 and 44-50, after reaction with tributyltin hydride or tris(trimethylsilyl)silane. Following standard procedures compound 44 was transformed into piperidinose derivative 54. These compounds are chiral, useful building blocks for the synthesis of glycosidase inhibitors of the fused-azole piperidinose type.