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5-Methyl-2-(3-trifluoromethyl-phenyl)-2H-pyrazol-3-ylamine is a complex organic chemical compound with the molecular formula C11H9F3N3. It is characterized by a pyrazole ring, which is a five-membered aromatic ring containing two nitrogen atoms, with a methyl group at the 5-position and a 3-trifluoromethyl-phenyl group attached at the 2-position. 5-METHYL-2-(3-TRIFLUOROMETHYL-PHENYL)-2H-PYRAZOL-3-YLAMINE is a derivative of pyrazole and is known for its potential applications in the synthesis of pharmaceuticals and agrochemicals due to its unique structure and reactivity. The presence of the trifluoromethyl group enhances the lipophilicity and metabolic stability of the molecule, which can be beneficial in drug design. However, it is important to note that the specific applications and safety profile of 5-METHYL-2-(3-TRIFLUOROMETHYL-PHENYL)-2H-PYRAZOL-3-YLAMINE would require further investigation and testing.

345-07-3

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345-07-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 345-07-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,4 and 5 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 345-07:
(5*3)+(4*4)+(3*5)+(2*0)+(1*7)=53
53 % 10 = 3
So 345-07-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H10F3N3/c1-7-5-10(15)17(16-7)9-4-2-3-8(6-9)11(12,13)14/h2-6H,15H2,1H3

345-07-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-methyl-2-[3-(trifluoromethyl)phenyl]pyrazol-3-amine

1.2 Other means of identification

Product number -
Other names 3-Methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:345-07-3 SDS

345-07-3Downstream Products

345-07-3Relevant academic research and scientific papers

Identification, design and synthesis of novel pyrazolopyridine influenza virus nonstructural protein 1 antagonists

Patnaik, Samarjit,Basu, Dipanwita,Southall, Noel,Dehdashti, Seameen,Wan, Kanny K.,Zheng, Wei,Ferrer, Marc,Taylor, Mercedes,Engel, Daniel A.,Marugan, Juan Jose

supporting information, p. 1113 - 1119 (2019/03/08)

Nonstructural protein 1 (NS1) plays a crucial function in the replication, spread, and pathogenesis of influenza virus by inhibiting the host innate immune response. Here we report the discovery and optimization of novel pyrazolopyridine NS1 antagonists that can potently inhibit influenza A/PR/8/34 replication in MDCK cells, rescue MDCK cells from cytopathic effects of seasonal influenza A strains, reverse NS1-dependent inhibition of IFN-β gene expression, and suppress the slow growth phenotype in NS1-expressing yeast. These pyrazolopyridines will enable researchers to investigate NS1 function during infection and how antagonists can be utilized in the next generation of treatments for influenza infection.

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