34501-45-6Relevant academic research and scientific papers
Synthesis, NMR spectra and X-ray data of chloro and dichloro derivatives of 3-hydroxy-2-phenylquinolin-4(1H)-ones and their cytostatic activity
Hradil, Pavel,Krejci, Petr,Hlavac, Jan,Wiedermannova, Iveta,Lycka, Antonin,Bertolasi, Valerio
, p. 375 - 379 (2004)
As known, some derivatives of quinolin-4(1H)-one possess interesting biological properties. The biological and cytostactic activity of 2-substituted 3-hydroxyquinolin-4(1H)-ones has not been reported yet. In this paper the synthesis of a series of chloro and dichloro 2-phenyl-3-hydroxyquinolin-4(1H)- ones and their characterization by NMR spectra and X-ray data is described. Their cytostatic properties have been evaluated and the results are reported.
