34504-00-2Relevant academic research and scientific papers
Highly efficient one-pot three-component Betti reaction in water using reverse zinc oxide micelles as a recoverable and reusable catalyst
Mou, Jie,Gao, Gan,Chen, Chen,Liu, Jie,Gao, Jian,Liu, Yi,Pei, Dongsheng
, p. 13868 - 13875 (2017/03/11)
An efficient synthesis of Betti bases via a one-pot three-component reaction of 2-naphthol, substituted aldehydes and anilines in aqueous media is reported. Through screening different catalysts, reverse zinc oxide nanomicelles show good activity and high
Novel and potent Lewis acid catalyst: Br2-catalyzed Friedel-Crafts reactions of naphthols with aldehydes
Liang, Deqiang,Li, Jingjing,Li, Yanni,Wang, Baoling,Cheng, Ping,Luo, Sha
supporting information, p. 379 - 385 (2016/03/23)
A discovery that the inexpensive Br2 can serve as a potent Lewis acid catalyst for bis(2-hydroxy-1-naphthyl)methanes synthesis is presented. Under the catalysis of Br2 at room temperature, naphthols reacted smoothly with various aldehydes with high efficiency and broad substrate scope. This reaction used to require highly acidic conditions and/or high temperature and/or pressure, and sometimes featured poor yields. Moreover, theoretical calculations suggested that Br2 is a potent Lewis acid to activate the carbonyl group, yet it was not the primary cause for the remarkable activity of Br2 in the current communication.
Investigation of keto-enol tautomers during the synthesis of aryl-bis (2-hydroxy-1-naphthyl)methanes
Dutta, Papia,Saikia, Mrinal,Das, Rashmi Jyoti,Borah, Ruli
, p. 1629 - 1634 (2015/02/05)
This study investigated the existence of keto-enol tautomers for the first time during the synthesis of aryl-bis(2-hydroxy-1-naphthyl)methane from 2-naphthol and p-tolualdehyde or 4-chlorobenzaldehyde in methanol using CuSO4.5H2O as catalyst under reflux condition. The exclusive formation of aryl-bis(2-hydroxy-1-naphthyl)methanes was observed in dichloromethane at room temperature in the presence of BF3.OEt2/AcOH as catalyst. The keto products were isolated and characterized by 1H NMR, 13C NMR, COSY and DEPT spectra. [Figure not available: see fulltext.]
1,3-Dibromo-5,5-dimethylhydantoin (DBH)/kaolin: An efficient reagent system for the synthesis of 14-aryl-14H-dibenzo[a,j]xanthenes under solvent-free conditions
Shirini, Farhad,Khaligh, Nader Ghaffari,Ghasem-Abadi, Parisa Ghods,Imanzadeh, Gholam Hossein
, p. 1145 - 1148,4 (2020/07/31)
1,3-Dibromo-5,5-dimethylhydantoin, has been used as an efficient catalyst for the synthesis of 14-aryl-14H-dibenzo[a,j]xanthenes in the presence of kaolin. All reactions are performed in the absence of solvent in relatively short reaction times in good to
Green and diasteroselective oxidative cyclization of bisnaphthols to spirans
Alizadeh,Khodaei,Moradi
experimental part, p. 351 - 358 (2010/09/03)
Hydrogen peroxide/MoO3, as an efficient and clean oxidizing system was used to afford diasteroselective oxidative cyclization of bisnaphthols to spirans in ethanol at 60 °C with high yields. Bisnaphthols were prepared by the reaction of a series of aldehydes and 2-naphthol in the presence of a catalytic amount of H3[P(Mo3O 10)4].nH2O (HPA) in refluxing dichloromethane.
A simple and efficient method for the synthesis of amidophenols using iodine as catalyst under neat condition
Selvam, Nagarajan Panneer,Perumal, Paramasivan T.
, p. 2972 - 2978 (2008/09/19)
A convenient and efficient one-pot synthesis of substituted amidophenols using iodine as catalyst at room temperature under neat condition is described.
Spirans. Part 12. Stereochemical Control in the Oxidative Cyclisation of Bisnaphthols
Bennett, David J.,Dean, Francis M.,Herbin, G. Antonio,Matkin, David A.,Price, Anthony W.,Robinson, Malcolm L.
, p. 1978 - 1985 (2007/10/02)
Almost all oxidising agents cyclise benzylidene-1,1'-bis-2-naphthol (1a) to the stereoisomers (2a) and (3a) of phenylnaphthofuran-2(1H)-spiro-1'(2'H)-naphthalen-2'-one.A few are stereospecific.Hypobromite and persulphate give (2a), whereas iodine oxyacids and (diacetoxyiodo)benzene are specific for (3a).Radical-type oxidants such as hexacyanoferrate(III) and 2,4-di-t-butyl-6-phenylphenoxyl (4) give mixtures.Horseradish peroxydase behaves like hexacyanoferrate(III).The presence in the benzylidene residue of methoxy, nitro, fluoro, and other groups has little effect upon the isomer ratios, which are believed to be determined mainly by the bulk of the benzylidene group and the limits it imposes upon conformations during the oxidation processes.Oxidation by (diacetoxyiodo)benzene occurs through a cyclic intermediate (9) and gives the less-hindered (3a); oxidation of hypobromite occurs not directly but by exchange through an aryl hypobromite (Scheme) which halogenates its opposite naphthol nucleus and then substitutes the halogen, with inversion, thus leading to the more-hindered isomer (2a).
