345264-21-3Relevant academic research and scientific papers
Preparation of novel aza-1,7-annulated indoles and their conversion to potent indolocarbazole kinase inhibitors
Al-awar, Rima S.,Ray, James E.,Hecker, Kyle A.,Joseph, Sajan,Huang, Jianping,Shih, Chuan,Brooks, Harold B.,Spencer, Charles D.,Watkins, Scott A.,Schultz, Richard M.,Considine, Eileen L.,Faul, Margaret M.,Sullivan, Kevin A.,Kolis, Stanley P.,Carr, Michael A.,Zhang, Faming
, p. 3925 - 3928 (2004)
The synthesis of novel aza-1,7-annulated indoles was achieved and these were converted to indolocarbazoles that proved to be potent kinase inhibitors. These compounds were also evaluated in a human colon carcinoma cell line and proved to be good antiproliferative agents.
PURINE DERIVATIVES AS KINASE INHIBITORS
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Page/Page column 38, (2008/06/13)
The present invention provides kinase inhibitors of Formula I.
