345306-07-2

Upstream product

• 2406-16-8 (R)-4-phenylpentane-1,4-diol 
• 88314-79-8 (R)-5-methyl-5-phenyl-3,4-dihydro(5H)-furan-2-one 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 345306-06-1 Acetic acid (R)-4-hydroxy-4-phenyl-pentyl ester 

Downstream Products

• 73464-88-7 (R)-2-phenyl-hexan-2-ol 
• 345306-10-7 tert-butyl-dimethyl-(1-methyl-1-phenyl-pentyloxy)-silane 
• 345306-11-8 tert-butyl-dimethyl-(1-methyl-1-phenyl-hexyloxy)-silane 
• 345306-09-4 toluene-4-sulfonic acid 4-(tert-butyl-dimethyl-silanyloxy)-4-phenyl-pentyl ester 
• 345306-08-3 4-(tert-butyl-dimethyl-silanyloxy)-4-phenyl-pentan-1-ol 

Relevant academic research and scientific papers

Efficient 1,8- and 1,9-asymmetric inductions in the Grignard reaction of δ- and ε-keto esters of 1,1′-binaphthalen-2-ols with an oligoether tether as the 2′-substituent: Application to the synthesis of (-)-malyngolide

Efficient 1,8- and 1,9-asymmetric inductions in the Grignard reaction of podand-type δ- (3,4) and ε-keto esters (5,6) are achieved in the presence of MgBr2·OEt2 with up to 97 and 82% optical yields, respectively, by using 2′-[3-(2-methoxyethoxy)propoxy]-1,1′-binaphthalen-2-ol as the chiral auxiliary. The 1,8-asymmetric inductive Grignard reaction has been advantageously utilized in the key step of a synthesis of (-)-malyngolide.