34547-21-2

Upstream product

• 16642-79-8 3-(4-nitrophenyl)propionic acid 
• 54405-42-4 methyl 3-(4-nitrophenyl)propanoate 

Downstream Products

• 1027357-16-9 5-methyl-3-[2-(4-nitrophenyl)-ethyl]-1H-[1,2,4]triazole 
• 1022171-46-5 2-[2-(4-nitrophenyl)ethyl]-5-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro naphthalen-2-yl)-1,3,4-oxadiazole 
• 1022171-57-8 3,5-di-tert-butyl-N'-[3-(4-nitrophenyl)propanoyl]benzohydrazide 
• 34547-15-4 5-(4-amino-phenethyl)-3H-[1,3,4]oxadiazol-2-one 
• 95060-15-4 3-(4-Nitro-phenyl)-propionic acid [2-oxo-1,2-dihydro-indol-(3Z)-ylidene]-hydrazide 
• 34544-61-1 5-(4-nitro-phenethyl)-3H-[1,3,4]oxadiazol-2-one 

Relevant academic research and scientific papers

Method for preparing compound intermediate for regulating cannabinoid receptor activity

The invention discloses a method for preparing a compound intermediate for regulating cannabinoid receptor activity. S1. a compound of formula IV is prepared by chloroformylation reaction of a compound of formula VI; S2. a compound of formula III is obtai

PHENYL DERIVATIVES AND THEIR USE AS A MEDICAMENT

The present invention relates to new phenylic derivatives exhibiting a good affinity for certain sub-types of cannabinoid receptors, in particular the CB2 receptors. These derivatives are of particular interest in a method for treating pathological conditions and diseases in which one or more cannabinoid receptors are involved. The invention also relates to pharmaceutical compositions containing said new phenylic derivatives and to methods for the preparation and use thereof.

5-OXO-5,8-DIHYDRO-PYRIDO-PYRIMIDINES AS INHIBITORS OF C-FMS KINASE

The invention addresses the current need for selective and potent protein tyrosine kinase inhibitors by providing potent inhibitors of c-fms kinase. The invention is directed to the novel compounds of Formula I: or a salt, stereoisomer, tautomer, crystalline, polymorph, amorphous, solvate, hydrate, ester, prodrug or metabolite form thereof, wherein A, Y, Z, R101 and R200 are described in the specification.

AGENT FOR PREVENTING OR TREATING NEUROPATHY

The present invention provides an agent for preventing or treating neuropathy having superior action and low toxicity. This agent comprises a compound represented by the formula:wherein ring A is a 5-membered aromatic heterocycle containing 2 or more nitrogen atoms, which may further have substituent(s);B is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group;X is a divalent acyclic hydrocarbon group;Z is -O-, -S-, -NR2-, -CONR2- or -NR2CO- (R2 is a hydrogen atom or an optionally substituted alkyl group);Y is a bond or a divalent acyclic hydrocarbon group;R1 is an optionally substituted cyclic group, an optionally substituted amino group or an optionally substituted acyl group, provided that when the 5-membered aromatic heterocycle represented by ring A is imidazole, then Z should not be -O-, or a salt thereof.