34547-93-8

Basic information

• Product Name: 3-Quinolinecarboxaldehyde, 4-hydroxy-2-methyl-
• CAS NO: 34547-93-8
• Molecular Formula: C11H9NO2
• Molecular Weight: 187.198
• Mol File: 34547-93-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 3-Quinolinecarboxaldehyde, 4-hydroxy-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Quinolinecarboxaldehyde, 4-hydroxy-2-methyl-(34547-93-8)
• EPA Substance Registry System: 3-Quinolinecarboxaldehyde, 4-hydroxy-2-methyl-(34547-93-8)

Safety Data

• Hazardous Substances Data: 34547-93-8(Hazardous Substances Data)

Upstream product

• 607-67-0 4-hydroxy-2-methylquinoline 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 90924-17-7 3,4-Dihydroxy-2-methyl-chinolin 
• 36826-09-2 5-methyl-3-phenyl-pyrano[3,2-c]quinolin-2-one 

Relevant articles and documents

Synthesis, antimicrobial activities and cytogenetic studies of newer diazepino quinoline derivatives via Vilsmeier-Haack reaction

The study of the Vilsmeier-Haack reagent on 4-hydroxyquinaldines resulted in a new versatile intermediate 4-chloro-3-formyl-2-(2-hydroxy-ethene-1-yl)quinolines, which on further treatment with hydrazine hydrate yielded the desired diazepino quinoline derivatives. All the synthesized diazepino quinoline derivatives are screened for their antibacterial and antifungal activities. Cytogenetic analysis of the samples is also reported.

Synthesis of 12-ethoxy-3-oxo-4-phenylquino[3,2-c][1,3]diazocines via Vilsmeier-Haack reaction

Application of Vilsmeier condition on 4-hydroxyquinaldines give potentially useful intermediates 4-chloro-3-formyl-2-(2-hydroxyethene-1-yl)quinolines, which are utilized to prepare quino[3,2-c][1,3]diazocines on treatment with N-phenylurea.

Vilsmeier-Haack reaction on quinaldines

The study of the Vilsmeier-Haack reaction on 4-hydroxyquinaldines resulted with the preparation of rarely existing 4-chloro-3-formyl-2(vinyl-1-ol)-quinolines.