34548-12-4Relevant academic research and scientific papers
An atom-economical protocol for direct conversion of Baylis-Hillman alcohols to β-chloro aldehydes in water
Bikshapathi, Raktani,Parvathaneni, Sai Prathima,Jayathirtha Rao, Vaidya
, p. 4446 - 4450 (2017)
This paper describes an atom-economical strategy for the direct conversion of Baylis-Hillman alcohols to β-chloro aldehydes under metal free conditions with excellent functional group tolerance. The use of stable-nontoxic Oxone as a terminal oxidant along with an inexpensive salt (sodium chloride) as a halogen source and water as the reaction medium makes this chemical synthetic process more viable and environmentally benign contributing towards green chemistry.
