34550-29-3Relevant academic research and scientific papers
Synthesis, antimicrobial activities and cytogenetic studies of newer diazepino quinoline derivatives via Vilsmeier-Haack reaction
Nandhakumar,Suresh,Jude, A.L. Calistus,Rajesh kannan,Mohan
, p. 1128 - 1136 (2008/03/12)
The study of the Vilsmeier-Haack reagent on 4-hydroxyquinaldines resulted in a new versatile intermediate 4-chloro-3-formyl-2-(2-hydroxy-ethene-1-yl)quinolines, which on further treatment with hydrazine hydrate yielded the desired diazepino quinoline derivatives. All the synthesized diazepino quinoline derivatives are screened for their antibacterial and antifungal activities. Cytogenetic analysis of the samples is also reported.
A novel approach to 12-chloro-3-thio-4H-quino[3,2-e][1,3]diazocines via Vilsmeier Haack reaction
Kumar, R. Nandha,Suresh,Dhanabal,Mohan
, p. 995 - 1000 (2008/09/18)
The Vilsmeier Haack reaction on 4-hydroxyquinaldines lead to potential intermediate 4-chloro-3-formyl-2-(2-hydroxyethene-1-yl)quinolines. The intermediate is further utilized to prepare quino[3,2-e][1,3]diazocines on treatment with thiourea. The structures of the new compounds are determined by the analytical and spectroscopic data.
Synthesis of 12-ethoxy-3-oxo-4-phenylquino[3,2-c][1,3]diazocines via Vilsmeier-Haack reaction
Kumar, Nandha,Suresh,Dhanabal,Mohan
, p. 598 - 601 (2007/10/03)
Application of Vilsmeier condition on 4-hydroxyquinaldines give potentially useful intermediates 4-chloro-3-formyl-2-(2-hydroxyethene-1-yl)quinolines, which are utilized to prepare quino[3,2-c][1,3]diazocines on treatment with N-phenylurea.
Utility of Vilsmeier Haack reagent in the synthesis of 3-amino-12-chloroquino[3,2-e][1,3]diazocines
Kumar, R. Nandha,Suresh,Dhanabal,Mohan
, p. 846 - 851 (2007/10/03)
Application of Vilsmeier condition on 4-hydroxyquinaldines gives a potential intermediate 4-chloro-3-formyl-2-(2-hydroxy-ethene-1-yl)quinolines which is utilized to prepare quino[3,2-e][1,3]diazocines on treatment with guanidine nitrate. All the synthesized compounds are characterized by the analytical and spectroscopic data.
Vilsmeier-Haack reaction on quinaldines
Nandha Kumar,Suresh,Mohan
, p. 2069 - 2073 (2007/10/03)
The study of the Vilsmeier-Haack reaction on 4-hydroxyquinaldines resulted with the preparation of rarely existing 4-chloro-3-formyl-2(vinyl-1-ol)-quinolines.
