345585-68-4

Upstream product

• 82500-48-9 6-(4-Chloro-phenoxy)-3-phenyl-1H-pyrimidine-2,4-dione 
• 68-12-2 N,N-dimethyl-formamide 
• 106-48-9 4-chloro-phenol 
• 5759-75-1 6-chloro-3-phenylpyrimidine-2,4(1H,3H)-dione 

Downstream Products

• 82500-55-8 6-Chloro-3-phenyl-9-oxa-1,3-diaza-anthracene-2,4-dione 

Relevant academic research and scientific papers

Synthesis of 2H-Chromenopyrimidine-2,4(3H)-diones (10-Oxa-5-deazaflavins) and Their Use in the Oxidation of Benzyl Alcohol

Treatment of 6-phenoxyuracil derivatives with the Vilsmeier reagent (dimethylformamide-phosphorous oxychloride)gave the corresponding 5-formyl-6-phenoxyuracil derivatives or their equivalents (5-dimethylaminomethylene-6-phenoxyuracil derivatives).Dehydrative cyclization of the above 5-formyluracils or 5-dimethylaminomethyleneuracils with polyphosphoric acid gave the corresponding 2H-chromenopyrimidine-2,4(3H)diones (10-oxa-5-deazaflavins).These 10-oxa-5-deazaflavins showed strong oxidizing power in oxidizing benzyl alcohol even under neutral conditions (without base) to give benzaldehyde, while they were hydrogenated to 1,5-dihydro-10-oxa-5-deazaflavins.