34572-26-4

Basic information

• Product Name: 1H-Benzimidazole-1-ethanol, a-phenyl-
• CAS NO: 34572-26-4
• Molecular Formula: C15H14N2O
• Molecular Weight: 238.289
• Mol File: 34572-26-4.mol

Chemical Properties

• CAS DataBase Reference: 1H-Benzimidazole-1-ethanol, a-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole-1-ethanol, a-phenyl-(34572-26-4)
• EPA Substance Registry System: 1H-Benzimidazole-1-ethanol, a-phenyl-(34572-26-4)

Safety Data

• Hazardous Substances Data: 34572-26-4(Hazardous Substances Data)

Upstream product

• 3282-32-4 2-diazo-acetophenone 
• 51-17-2 benzoimidazole 
• 70-11-1 α-bromoacetophenone 
• 96-09-3 styrene oxide 
• 89101-27-9 2-( 1H-benzo[d]imidazol-1-yl)-1-phenylethanone 

Downstream Products

• 1013325-34-2 benzoic acid 2-(benzimidazol-1-yl)-1-phenylethyl ester 

Relevant articles and documents

Solvent-free direct regioselective ring opening of epoxides with imidazoles

The reaction of different epoxides with commercially available imidazole at 60 °C leads to the formation of the corresponding 1-(β-hydroxyalkyl)imidazoles in a regioselective manner. When the reaction is applied to a chiral epoxide [(R)-styrene oxide], th

Synthesis and antimicrobial activity of some novel phenyl and benzimidazole substituted benzyl ethers

In this study, a series of novel phenyl- and benzimidazole-substituted benzyl ethers were synthesized and evaluated for antibacterial and antifungal activities against Staphylococcus aureus, Methicillin-resistant S. aureus (MRSA), Escherichia coli, Candid

Eco-friendly synthesis and antifungal evaluation of N-substituted benzimidazoles

Abstract: A convenient synthesis of N-phenacylbenzimidazoles in high yields (90–95%) by the N-alkylation reaction of 1H-benzimidazole with phenacyl bromides is provided. The carbonyl group reduction in the products offered the respective N-(2-aryl-2-hydroxyethyl)benzimidazoles in yields up to 97%. In the optimization of reaction conditions for preparing these N-substituted benzimidazoles (ketones and alcohols), a comparative study between eco-friendly methods (microwave and ultrasound) and conventional heating is described. These antifungal azoles analogs were tested for in vitro antifungal activity against Candida albicans and Cryptococcus neoformans, where the alcohols chlorine substituted (4-Cl and 2,4-Cl2) showed the best activity (MIC50 = 31.2 × 10–6 g/cm3). Graphic abstract: [Figure not available: see fulltext.]

Synthesis, in vitro antifungal evaluation and docking studies of novel derivatives of imidazoles and benzimidazoles

A series of imidazole and benzimidazole derivatives was designed and prepared in good yields via convenient and efficient two steps synthetic route using readily available starting materials. The structures of the synthesized compounds and their intermedi