3458-34-2

Usage

Hydraiodide salt derivative

The compound is derived from 1-amino-3-benzylguanidine by the addition of hydriodide (HI), which forms a salt.

Potent inhibitor of OCT2

1-Amino-3-benzylguanidine, hydriodide is a strong inhibitor of the human organic cation transporter OCT2, which plays a role in the transport of organic cations across cell membranes.

Potential use in treating hypertension

The compound has been studied for its ability to lower blood pressure in individuals with hypertension.

Potential use in treating heart failure

Research has explored the use of 1-Amino-3-benzylguanidine, hydriodide in improving heart function and managing heart failure symptoms.

Potential use in treating kidney disease

The compound has been investigated for its possible benefits in managing kidney disease and improving kidney function.

Neuroprotective agent

1-Amino-3-benzylguanidine, hydriodide has been studied for its potential to protect neurons in cases of cerebral ischemia (reduced blood flow to the brain) and stroke.

Potential anti-tumor activity

The compound has been researched for its possible ability to inhibit the growth of certain types of cancer cells.

Medical and pharmaceutical applications

Due to its various potential uses, 1-Amino-3-benzylguanidine, hydriodide may have future applications in the medical and pharmaceutical industries.

Upstream product

• 35600-34-1 S-methylisothiosemicarbazide hydroiodide 
• 100-46-9 benzylamine 
• 35600-34-1 S-methyl isothiosemicarbazide hydroiodide 
• 79-19-6 thiosemicarbazide 

Downstream Products

• 1242050-29-8 C₁₀H₁₁N₅O 
• 1284312-78-2 2-amino-5-(benzyl)imidazo[1,2-b][1,2,4]triazine-3,6,7(5H)-trione 
• 1242050-39-0 C₁₃H₁₅N₅O₃ 
• 1242050-40-3 C₁₈H₁₇N₅O₃ 
• 3458-35-3 1-Benzyl-3-benzylidenamino-guanidin 
• 86410-13-1 1-benzyl-3-<<4-(hexadecylamino)benzylidene>amino>guanidine 
• 5369-92-6 3-amino-4-benzyl-1,2,4-triazole 

Relevant academic research and scientific papers

AMINOGUANIDINE HYDRAZONES AS RETROMER STABILIZERS USEFUL FOR TREATING NEUROLOGICAL DISEASES

The present invention relates to novel aminoguanidine hydrazone-derivatives of Formula (I) which are effective as retromer stabilizers and useful as neuroprotecting drugs. The invention also relates to pharmaceutical compositions comprising the compounds and their use in therapy and diagnostic.

NOVEL 5-HT2 ANTAGONISTS

The present invention relates to 1-amidino-3-aryl-2-pyrazoline derivatives of the general formula I The invention specifically relates to such derivatives which exhibit antagonizing activity towards serotonin 5-HT2B receptors. The present invention also relates to use of said compounds as a medicament and for the treatment of fibrosis, cardiovascular diseases, pain, IBD, and other inflammatory diseases, as well as pharmaceutical compositions comprising one or more of said compounds and methods of treatment.

Synthesis and properties of 3,6-diamino-substituted 1,2,4-Triazin-5(2H)- ones

The ultrasound-promoted cyclocondensation of N1-amino-N 2-arylmethyl-(or aryl-) guanidines 2 with ethyl 2-amino-2- thioxoacetate furnished novel 3,6-diamino-substituted 1,2,4-triazin-5(2H)- ones 4 in moderate to high yields. The acyl

Aminoguanidine derivatives

A aminoguanidine derivatives of the general formula: (wherein, R1brepresents a hydrogen atom, alkyl group of from 1 to 6 carbon atom(s), cycloalkyl group of from 5 to 7 carbon atoms or carbocyclic or heterocyclic ring unsubstituted or substitut

Synthesis and biological activity of guanylhydrazones of 2- and 4-pyridine and 4-quinoline carboxaldehydes

A series of guanylhydrazones derived from 2- and 4-pyridine and 4-quinoline carboxaldehydes was synthesized from S-methylisothiosemicarbazide hydroiodide using known procedures. The compounds are analogous to anticancer and antiviral thiosemicarbazones, b

Substituted 9,10-anthracenebishydrazones

This disclosure describes anthracene-9,10-bis-carbonyl-hydrazones and derivatives thereof useful as antibacterial agents, for inhibiting the growth of transplanted mouse tumors, and for inducing the regression and/or palliation of leukemia and related cancers.