34582-84-8Relevant academic research and scientific papers
Design, synthesis, analgesic, anti-inflammatory activity of novel pyrazolones possessing aminosulfonyl pharmacophore as inhibitors of COX-2/5-LOX enzymes: Histopathological and docking studies
Abdelgawad, Mohamed A.,Labib, Madlen B.,Ali, Waleed A.M.,Kamel, Gehan,Azouz, Amany A.,EL-Nahass, EL-Shaymaa
, p. 103 - 114 (2018)
A series of newly synthesized 4-aryl-hydrazonopyrazolones were designed and their structures were confirmed by spectral and elemental analyses. All synthesized compounds were evaluated for their in vitro COXs, 5-LOX inhibition, in vivo analgesic and anti-
