34586-27-1

Basic information

• Product Name: 1-(1-CHLOROETHYL)-3-NITROBENZENE
• Synonyms: Benzene, 1-(1-chloroethyl)-3-nitro-
• CAS NO: 34586-27-1
• Molecular Formula: C₈H₈ClNO₂
• Molecular Weight: 185.61
• Mol File: 34586-27-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 261.904°C at 760 mmHg
• Flash Point: 112.196°C
• Appearance: /
• Density: 1.269g/cm³
• Vapor Pressure: 0.018mmHg at 25°C
• Refractive Index: 1.559
• CAS DataBase Reference: 1-(1-CHLOROETHYL)-3-NITROBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-CHLOROETHYL)-3-NITROBENZENE(34586-27-1)
• EPA Substance Registry System: 1-(1-CHLOROETHYL)-3-NITROBENZENE(34586-27-1)

Safety Data

• Hazardous Substances Data: 34586-27-1(Hazardous Substances Data)

Usage

Type of compound

Nitroaromatic

Uses

Production of dyes, pharmaceuticals, and agrochemicals

Structure

Benzene ring with a chloroethyl group and a nitro group attached

Physical appearance

Yellow to orange crystalline solid

Flammability

Flammable

Health hazards

Potential skin, eye, and respiratory system irritation

Safety classification

Hazardous chemical, should be handled with care

InChI:InChI=1/C8H8ClNO2/c1-6(9)7-3-2-4-8(5-7)10(11)12/h2-6H,1H3

Upstream product

• 121-89-1 3-Nitroacetophenone 
• 5400-78-2 1-(3-nitrophenyl)ethanol 

Downstream Products

• 586-39-0 1-nitro-3-vinyl-benzene 
• 1190378-94-9 cyclobutanecarboxylic acid (3-{5-cyclopropyl-2-[3-(1-morpholin-4-yl-ethyl)-phenylamino]-pyrimidin-4-ylamino}-propyl)-amide 
• 1082549-24-3 3-(1-morpholin-4-yl-ethyl)-phenylamine 
• 1190371-32-4 4-[1-(3-nitro-phenyl)-ethyl]-morpholine 

Relevant articles and documents

Ferric chloride–catalyzed deoxygenative chlorination of carbonyl compounds: A comparison of chlorodimethylsilane and dichloromethylsilane system

Deoxygenative chlorination of carbonyl compounds using the HMe2SiCl/FeCl3/EtOAc and HMeSiCl2/FeCl3/EtOAc systems has been systemically investigated. The HMe2SiCl-FeCl3 system showed the advantages of good substrate applicability, mild reaction conditions, simple operation, low cost, and easy availability of raw materials. Also, it provided a simple and efficient synthesis route for carbonyl deoxychlorination via a one-pot method. Using the HMeSiCl2/FeCl3/EtOAc system, the β-methylchalcone derivative could be obtained in good yields in addition to obtaining the chlorinated compound. Finally, two plausible reaction routes were proposed to describe the formation of the chlorinated compound and the β-methylchalcone derivative.

Nitrobenzyl monates antibacterial compounds

Compounds of formula (II): STR1 wherein Y is --CH=CH--CH2 --CH-- or STR2 R1 is hydrogen or C1-4 alkyl, R2 is hydrogen or C1-6 alkyl, R3 is hydrogen, nitro or C1-6 alkyl and, when